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MaxCard:
CAS NO.95635-56-6
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|
anolazine dihydrochloride Basic information |
Product Name: | Ranolazine dihydrochloride |
Synonyms: | (+/-)-4-[2-HYDROXY-3-(O-METHOXYPHENOXY)PROPYL]-1-PIPERAZINEACETO-2',6'-XYLIDIDE DIHYDROCHLORIDE;n-(2,6-dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide dihydrochloride;(+/-)-N-(2,6-DIMETHYLPHENYL)-4-[2-HYDROXY-3-(2-METHOXYPHENOXY)PROPYL]-1-PIPERAZINEACETAMIDE DIHYDROCHLORIDE;RANOLAZINE DIHYDROCHLORIDE;RANOLAZINE HCL;Ranolazine DiHCI;Ranolazine and salt;(±)-N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide |
CAS: | 95635-56-6 |
MF: | C24H35Cl2N3O4 |
MW: | 500.46 |
EINECS: | |
Product Categories: | Active Pharmaceutical Ingredients;Aromatics Compounds;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Ranolazine;Cardiovascular APIs |
Mol File: | 95635-56-6.mol |
Ranolazine dihydrochloride Chemical Properties |
mp | 222-229.5 °C(lit.) |
storage temp. | Desiccate at RT |
solubility | H2O: 10 mg/mL, soluble |
form | solid |
color | off-white |
CAS DataBase Reference | 95635-56-6(CAS DataBase Reference) |
Safety Information |
Safety Statements | 22-24/25 |
WGK Germany | 3 |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
Ranolazine dihydrochloride Usage And Synthesis |
Chemical Properties | White Crystalline Powder |
Usage | Anti-ischemic agent which modulates myocardial metabolism. Antianginal |
Usage | treatment of angina and congestive heart failure |
Biological Activity | Antianginal agent with antiarrhythmic properties that acts as a partial fatty acid oxidation inhibitor. Activates pyruvate dehydrogenase in ischemic myocytes to promote glucose oxidation, switching substrate utilization from fatty acids to glucose. Also shown to inhibit late I Na and I Kr currents. |
Ranolazine dihydrochloride Preparation Products And Raw materials |