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Tel: 17734809689
Tel: 86-371-86259723
Tel: 17734809689
Tel: 17734809689
Mobile: 17734809689
Tel: +86-371- 86259723
Fax: +86-371- 86259723
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MaxCard:
CAS NO.94055-76-2
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Suplatast tosilate Basic information |
Product Name: | Suplatast tosilate |
Synonyms: | (2-(4-(3-ethoxy-2-hydroxypropoxy)phenylcarbamoyl)ethyl)dimethylsulfonium p-toluenesulfonate;SUPLATAST TOSILATE;Suplatast tosylate;Suplatast;2-[4-(2-Hydroxy-3-ethoxypropoxy)phenylcarbamoyl]ethyldimethylsulfonium·4-methylbenzenesulfonate;IPD-1151T;S,S-Dimethyl-3-oxo-3-[4-(2-hydroxy-3-ethoxypropoxy)anilino]propane-1-sulfonium·4-methylbenzenesulfonate;[2-[[[4-(2-Hydroxy-3-ethoxypropoxy)phenyl]amino]carbonyl]ethyl]dimethylsulfonium |
CAS: | 94055-76-2 |
MF: | C23H33NO7S2 |
MW: | 499.64062 |
EINECS: | |
Product Categories: | API;Aromatics;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;IPD 1151T |
Mol File: | 94055-76-2.mol |
Suplatast tosilate Chemical Properties |
Melting point | 84-87°C |
storage temp. | Store at RT |
CAS DataBase Reference | 94055-76-2(CAS DataBase Reference) |
Safety Information |
Suplatast tosilate Usage And Synthesis |
Usage | Suplatast Tosylate is an antiallergic drug. Suplatast Tosylate inhibits antigen-induced histamine release from mast cells as well as IgE antibody formation. Suplatast Tosylate suppresses interleukin (IL)-4 release from T cells, however in human peripheral basophils, Suplatast Tosylate inhibited the antigen-induced release of IL-13 but not IL-4. |
Usage | Suplatast Tosilate is a novel capsular anti-asthmatic agent that suppresses both IgE production, IL-4 and IL-5 synthesis with IC50 above 100 μM. |
Biological Activity | Th2 cytokine inhibitor that attenuates IL-2, IL-5 and IL-13 production and has no effect on IFN- γ production. Acts as an immunoregulator that suppresses IgE production, eosinophil infiltration and histamine release. Exhibits antiasthmatic, anti-inflammatory and antifibrotic activity in vivo and is orally active. |
Suplatast tosilate Preparation Products And Raw materials |
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