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CAS NO.93479-97-1
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Glimepiride Basic information |
Product Name: | Glimepiride |
Synonyms: | 1h-pyrrole-1-carboxamide,2,5-dihydro-3-ethyl-4-methyl-n-(2-(4-(((((4-methylcyc;glimepirid;hoe490;trans-lohexyl)amino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-oxo;GLIMEPIRIDE;1-[[p-[2-(3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(trans-4-methylcyclohexyl)urea;amary;AMARYL |
CAS: | 93479-97-1 |
MF: | C24H34N4O5S |
MW: | 490.62 |
EINECS: | |
Product Categories: | Active Pharmaceutical Ingredients;APIs;Intermediates & Fine Chemicals;Pharmaceuticals;Monovalent Ion Channels;Potassium Channel Modulators;Voltage-gated Ion Channels;API's;Chiral Reagents;Heterocycles;Sulfur & Selenium Compounds;API;NEURONTIN;Diabetes Research |
Mol File: | 93479-97-1.mol |
Glimepiride Chemical Properties |
mp | 212.2-214.5 °C |
storage temp. | Room temp |
solubility | DMSO: >10 mg/mL |
form | solid |
color | white |
CAS DataBase Reference | 93479-97-1(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xn,Xi |
Risk Statements | 21-36/38-46-62-63 |
Safety Statements | 25-26-36/37-53 |
WGK Germany | 3 |
RTECS | UX9363950 |
MSDS Information |
Provider | Language |
---|---|
Amary | English |
SigmaAldrich | English |
Glimepiride Usage And Synthesis |
Chemical Properties | White Cyrstalline Solid |
Usage | anticonvulsant |
Usage | For concomitant use with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus. |
Usage | A sulfonylurea hypoglycemic agent. Used as an antidiabetic |
Biological Activity | Potent K ATP channel blocker and anti-diabetic agent. Inhibits pinacidil-activated cardiac K ATP channels with an IC 50 of 6.8 nM. |
Glimepiride Preparation Products And Raw materials |
Raw materials | Pyrrole-->Methyl carbamate-->Phenylethyl isocyanate |