HENAN SUNLAKE ENTERPRISE CORPORATION
Free supplier Enterprise Certification
- Free
supplier - 9th
years
Free supplier Enterprise Certification
Product Certification&
Enterprise Certification
Country: 
China (Mainland)
Business Type:Trading Company
Tel: +86-371- 86259723
Tel: 17734809689
Tel: 17734809689
Tel: 86-371-86259723
Tel: 17734809689
Tel: 17734809689
Mobile: 17734809689
Tel: +86-371- 86259723
Fax: +86-371- 86259723
Province/state: HENAN
City: ZHENGZHOU
Street: Mingmen International Center, NO.222 Dongming Road,Zhengzhou,Henan,China
MaxCard:
Contact Suppliers
CAS NO.934660-93-2
1(10-100)Metric Ton1(10-100)Metric Ton
| XL518 Basic information |
| Product Name: | XL518 |
| Synonyms: | XL518;GDC-0973;RG7420;[3,4-difluoro-2-[(2-fluoro-4-iodophenyl)aMino]phenyl][3-hydroxy-3-[(2S)-2-piperidinyl]-1-azetidinyl]Methanone;GDC-0973(XL-518);(S)-(3,4-difluoro-2-(2-fluoro-4-iodophenylaMino)phenyl)(3-hydroxy-3-(piperidin-2-yl)azetidin-1-yl)Methanone;XL518 ,GDC-0973;CobiMetinib |
| CAS: | 934660-93-2 |
| MF: | C21H21F3IN3O2 |
| MW: | 531.3100196 |
| EINECS: | |
| Product Categories: | Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Protein Kinase Inhibitors and Activators;API |
| Mol File: | 934660-93-2.mol |
|
|
|
| XL518 Chemical Properties |
| density | 1.706 |
| Safety Information |
| XL518 Usage And Synthesis |
| Usage | A potent, selective, orally bioavailable inhibitor of MEK1, a component of the RAS/RAF/MEK/ERK pathway. It inhibits proliferation and stimulates apoptosis in a variety of human tumor cell lines. In preclinical xenograft models, oral administration of XL518 results in sustained inhibition of pERK in tumor tissue, but not brain tissue, leading to tumor growth inhibition and regression at well tolerated doses. |
We have clients throughout the world：
Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet your desire.
Our Laboratoy
We have our own independent lab test center：
This makes sure that our technology support is reliable and authoritative.All of self-owned fine chemicals are manufactured strictly in accordance with international standard.,and also has scientific cooperation with local colleges and institutes.
Our factory
High quality with competitive price：
We are manufacturer and can provide high quality products with factory price
Package & Shipment
Fast and safe delivery：
Parcels can be sent out within 24 hours after payment. Tracking number is available
Secure and discreet shipment. You have various choices of transportation methods
