Keywords

• Ginkgo biloba extract
• 90045-36-6
• 90045-36-6

Quick Details

• ProName: Ginkgo biloba extract 90045-36-6
• CasNo: 90045-36-6
• Molecular Formula: 90045-36-6
• Appearance: detailed in specifcations
• Application: Aripiprazole Intermediate plant extr...
• DeliveryTime: within 5days
• PackAge: as needed
• Port: China main port
• ProductionCapacity: 500 Metric Ton/Month
• Purity: 99%
• Storage: Keep in dry and cool condition
• Transportation: by air or sea
• LimitNum: 1 Kilogram
• MF: C13H21O3PS

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Company information

Henan Sunlake Enterprise Corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs , Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East , Africa , South America and some other countries and areas.We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you better with our high - quality products and professional team.We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.We welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate.

Details

Ginkgo biloba extract Basic information

Plant Extract Chemical Composition Plant Sources Cardiovascular disease treatment Extracting Method Pharmacological activity Pharmacokinetics Toxicity and Side Effect Drug Interactions Applications

Product Name:	Ginkgo biloba extract
Synonyms:	Ginkgobiloba,ext.;ginkgobilobal.,rootextract;yajiaotong;GINKGO BILOBA;GINKGO BILOBA EXTRACT;Ginkgo Biloba Extract Powder;24/6 GINKGO BILOBA EXTRACT 24/6;Ginkgo biloba leaves tea bag cut
CAS:	90045-36-6
MF:
MW:	0
EINECS:	289-896-4
Product Categories:	Nutritional Supplements;Beauty;plant extract;Nutritional Ingredients
Mol File:	Mol File

Ginkgo biloba extract Chemical Properties

CAS DataBase Reference

90045-36-6(CAS DataBase Reference)

Safety Information

MSDS Information

 

Ginkgo biloba extract Usage And Synthesis

Plant Extract	Ginkgo biloba extract is the dried leaf extract of Ginkgo ginkgo species Ginkgo (GinkgobilobaL) Its main component is flavonoids and terpene lactones and has a variety of health functions. It is widely used in food and cosmetics. The above information is edited by the Chemicalbook of Dai Xiongfeng.
Chemical Composition	The leaf Ginkgo biloba has a complex chemical composition. People has isolated out more than 140 kinds of compounds from it. Flavonoids and terpene lactones compound are the two main functional components. Ginkgo flavonoid is also known as single flavonoids, mainly as glycosidase form of kaempferol, quercetin and isorhamnetin. Ginkgolides belongs to a terpene, consists of the times of abundant terpene lactones and diterpene lactone, further mainly as ginkgo esters and ginkgolide. Besides, it also contains Polyprenols, organic acids, polysaccharides, amino acids, phenols and trace elements.
Plant Sources	Ginkgo biloba is an ancient and primitive larvae relic species. It has been growing on earth about 200 million years, as a "living fossil". China is the hometown of ginkgo, the current Chinese ginkgo resources accounted for 70% of the world. Dating back to "Daily Materia Medica" published in 14th century, Ginkgo have already been used a Chinese herbal medicine folk use, first appeared in the fourteenth century among folks, mainly used for treating cough, asthma and inflammation. Ginkgo biloba, also known as duck feet, maidenhair tree, tree duck, is deciduous trees as high as 40m. It has a erecting trunk and gray bark. It has both short and long branches with leaves clustering on short branches and alternating in long branches. It has fan blades with length 4 ~ 8cm, width 5 ~ 10cm. Its seed is named “Baiguo”. Ginkgo is mainly distributed in latitude 19° 40 ~ 43° 40, longitude 97° 00 ~ 126°30, with a average annual temperature of 14 °C ~ 18 °C. It grows well in a cool but warm winter and spring, and a humid and warm summer and fall. It is susceptible to frost damage in the cold of winter ( the following -20°C). It also grows poorly in tropic areas with long-term summer but no winter. Ginkgo biloba is widely distributed in China, located from the middle of China to the west. You can also find it in north place such as Liaoning, south place such as Guangdong, east place such as Taiwan, west place Qinghai are planted. It is mainly planted at Jiangsu, Shandong, Zhejiang, Hubei provinces. Now it has also been introduced into Japan and United States. Figure 1. Leaves and seeds of Ginkgo biloba (ginkgo)
Cardiovascular disease treatment	Ginkgo biloba extract is a commonly used traditional Chinese medicine for the treatment of cardiovascular and cerebrovascular diseases. Its main functional ingredient is ginkgo flavonoids and ginkgo diterpenoid lipid compounds, wherein the flavonoids including quercetin glycosides, kaempferol, iso-buckthorn Su. Ginkgo diterpene lipid component includes ginkgolides A, B, C, J, M and bilobalide. Ginkgo biloba extract has antioxidant activity, cardiovascular activity, anti-inflammatory activity and anti-tumor effect. It can not only expand cardiovascular and arteries, but also protect microvascular well, thus effectively preventing vascular blockage of blood vessels and having a good precaution effect against hyperlipaemia, hypertension, diabetes and so on. Moreover, it also indirectly reduce the common eye diseases (cataract, glaucoma, vitreous opacity, retinopathy, diabetes-concurrent eye diseases, etc.). On one hand, it effectively cleans the blood, strengthens the blood vessels, prevents and treats cardiovascular disease. On the other hand, it is also effective in treating brain mal-function, anti-aging, preventing cancer. For the last 10 years, American consumers have been taking the product of ginkgo biloba as health food for preventing stroke and coronary heart disease. According to recent reports the American Journal of Medicine, during a over 3-years clinic studies, researchers from Oregon State University, Department of Medicine found that, taking Ginkgo biloba is very effective in preventing memory recession and Alzheimer's disease for over 65-years old men.
Extracting Method	According to incomplete statistics, the current international standard of Ginkgo biloba extract is product EGb761 produced by the Schwabe patented technology of the German. The appearance is brown powder with a slight smell of ginkgo biloba. Ginkgo biloba extract of Ginkgo biloba is extracted with GinkgobilobaL leaves as raw material. Commercially extracts are usually marked as containing 24% flavonoid glycosides, ginkgolides 6%. There are many reports and literatures on productive technology of Ginkgo biloba extract, mainly including in the acetone extraction & lead salt precipitation, ethanol extraction & macroporous resin adsorption separation, supercritical carbon dioxide extraction, alcohol extraction& Extraction & chromatography, etc., Domestic production mainly apply ethanol extraction - resin separation. Organic solvent extraction is the mostly widely used approach. Owing to the significant toxicity and volatility of other organic solvents, people generally take ethanol as the extraction agent. Zhang Yonghong et al, showed that a good extraction condition of Ginkgo biloba extract is using 70% ethanol as extraction agent with extraction temperature 90 °C, solid-liquid ratio 1:20, 3 times extraction with a 1.5 h reflux for each time. 1. Ethanol Extraction & macroporous resin separation Remove Mildew leaves and impurities, wash, chopped and extract with 70% ethanol reflux, fractionate the extract, filtrate, decompress to recycle the ethanol, remove the debris by high-speed centrifugation, add certain amount water for dilatation and add into macroporous resin column. Elute the mixture with water until the eluents become clear. Further elute by a certain concentration of ethanol and collect the eluents. Concentrate it under reduced pressure and vacuum dry it to obtain the final extract. 2. The acetone extract - lead hydroxide precipitation Extract the Ginkgo biloba leaves with 60% acetone. Filter after cooling, extract with carbon tetrachloride, then add ethyl ketone and mix to separate out the acetone - butanone phases, add solid ammonium sulfate to the phase and stir for filtering off solid substance. Decompress and evaporate the filtrate to a concentration that containing 20%-60% solid. Use 50% denatured ethanol to dilute it to a concentration of 10% solid. Add lead hydroxide suspension and filter off the precipitate. The filtrate was decompressed and concentrated to half volume and then added ammonia sulfate and methyl ethyl ketone under stirring, The butanone - ethanol phase comes out after stirring; Separate out butanone-ethanol from the aqueous phase, and then add butanone into the aqueous phase, stir to separate butanone - ethanol phase for the 2nd time. Combine the two times butanone - ethanol phase above, add ammonium sulfate under stirring, mix