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Fluticasone propionate

CAS NO.80474-14-2

  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,Other
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Product Details

Keywords

  • s-fluoromethyl-6alpha,9alpha-difluoro-11beta-hydroxy-16alpha-methyl-3-oxo-17alpha-propionyloxyandrosta-1,4-diene-17beta-carbothioate
  • -17-(1-oxopropoxy)-,s-(fluoromethyl)ester,(6-alpha,11-beta,16-alpha,17-alph
  • androsta-1,4-diene-17-carbothioicacid,6,9-difluoro-11-hydroxy-16-methyl-3-oxo

Quick Details

  • ProName: Fluticasone propionate
  • CasNo: 80474-14-2
  • Molecular Formula: C25H31F3O5S
  • Appearance: Crystalline Solid
  • Application: Usage An antiallergic and anti inflamm...
  • DeliveryTime: within 3-7 days
  • PackAge: depended
  • Port: shanghai port
  • ProductionCapacity: 200 Kilogram/Month
  • Purity: 98%
  • Storage: Store in dry, dark and ventilated plac...
  • Transportation: by air or by sea
  • LimitNum: 1 Kilogram

Superiority

 


Preview
CBNumber: CB1252206
Chemical Name: Fluticasone propionate
Molecular Formula: C25H31F3O5S
Formula Weight: 500.57
CAS No.: 80474-14-2

 

Details

Fluticasone propionate Basic information
Product Name: Fluticasone propionate
Synonyms: s-fluoromethyl-6alpha,9alpha-difluoro-11beta-hydroxy-16alpha-methyl-3-oxo-17alpha-propionyloxyandrosta-1,4-diene-17beta-carbothioate;-17-(1-oxopropoxy)-,s-(fluoromethyl)ester,(6-alpha,11-beta,16-alpha,17-alph;androsta-1,4-diene-17-carbothioicacid,6,9-difluoro-11-hydroxy-16-methyl-3-oxo;cci18781;fluticasone17-propionate;flutide;(6A,11B,16A,17A)-6,9-DIFLUORO-11-HYDROXY-16-METHYL-3-OXO-17-(1-OXOPROPOXY)ANDROSTA-1,4-DIENE-17-CARBOTHIOIC ACID FLUOROMETHYL ESTER;(6 ALPHA,11 BETA,16 ALPHA,17 ALPHA)-6,9-DIFLUORO-11-HYDROXY-16-METHYL-3-OXO-17-(1-OXOPROPOXY)ANDROSTA-1,4-DIENE-17-CARBOTHIOIC ACID FLUOROMETHYL ESTER
CAS: 80474-14-2
MF: C25H31F3O5S
MW: 500.57
EINECS:  
Product Categories: Biochemistry;Hydroxyketosteroids;Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Fluticasone;Steroid and Hormone;HIVID;Hormone Drugs
Mol File: 80474-14-2.mol
Fluticasone propionate Structure
 
Fluticasone propionate Chemical Properties
mp  275 °C
refractive index  31 ° (C=1, Dioxane)
storage temp.  Store at RT
solubility  DMSO: ≥10 mg/mL
form  solid
color  white
Merck  4211
CAS DataBase Reference 80474-14-2(CAS DataBase Reference)
 
Safety Information
Safety Statements  22-24/25
WGK Germany  2
RTECS  BV7980000

 

Fluticasone propionate Usage And Synthesis
Chemical Properties Crystalline Solid
Usage An antiallergic and anti inflammatory
Usage A derivative of Flumethasone. An antiallergic; anti-asthmatic; anti-inflammatory.
Usage antiviral
Usage Atorvastatin Intermediate
Usage A high-affinity, selective glucocorticoid receptor agonist
Biological Activity High affinity, selective glucocorticoid receptor agonist (K d = 0.5 nM). Potently stimulates glucocorticoid receptor-mediated transactivation of gene expression and enhances human eosinophil apoptosis (EC 50 = 3.7 nM) in vitro . Inhibits mast cell accumulation in nasal mucosa following topical administration. Lipophilic, clinically-used anti-inflammatory agent with low oral bioavailability.

 

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