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Tel: 17734809689
Tel: 86-371-86259723
Tel: 17734809689
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Tel: +86-371- 86259723
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CAS NO.80214-83-1
Roxithromycin Basic information |
Product Name: | Roxithromycin |
Synonyms: | ROXITHROMYCIN;ERYTHROMYCIN 9-(-O-[2-METHOXYETHOXY]METHYLOXIME);ERYTHROMYCIN, 9-[O-[(2-METHOXYETHOXY)METHYL]OXIME], (9E)-;Roxithromycin CP2000;Roxithromycin EP;RoxithromycinEp/Bp/CpC41H76N2O15;RoxithromycinC41H76N2O15;(9E)-9-[O-[(2-Methoxyethoxy)methyl]oxime] Erythromycin |
CAS: | 80214-83-1 |
MF: | C41H76N2O15 |
MW: | 837.05 |
EINECS: | |
Product Categories: | Antibiotic Explorer;Intermediates & Fine Chemicals;Pharmaceuticals;veterinary medicine,soluble powder;Peptide Synthesis/Antibiotics;Chiral Reagents |
Mol File: | 80214-83-1.mol |
Roxithromycin Chemical Properties |
mp | 111-118 C |
storage temp. | 2-8°C |
Roxithromycin Usage And Synthesis |
Chemical Properties | White Solid |
Usage | anesthetic (local) |
Usage | Roxithromycin was one of the new generation erythromycins introduced in the 1980s. Improved acid stability was achieved by converting the 9-keto group to the more stable oxime and alkylation of the oxime to provide the methoxyethoxymethyl ether oxime. In vivo, roxithromycin exhibits higher tissue levels and a longer half-life while being slightly less potent than erythromycin in vitro. |
Usage | Semisynthetic erythromycin derivative. Antibacterial |
Roxithromycin Preparation Products And Raw materials |
Raw materials | Etanol-->Methanol-->N,N-Dimethylformamide-->Triethylamine-->Hydroxylamine hydrochloride-->Erythromycin-->2-Methoxyethoxymethyl chloride |
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