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CAS NO.78755-81-4
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Flumazenil Basic information |
Product Name: | Flumazenil |
Synonyms: | ethyl 8-fluoro-5-methyl-6-oxo-5,6-dihydro-4h-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate;FLUMAZENIL;8-FLUORO-5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A][1,4]BENZO-DIAZEPINE-3-CARBOXYLIC ACID ETHYL ESTER;8-FLUORO-5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A][1,4]BENZODIAZEPINE-3-CARBOXYLIC ACID ETHYL EST;4H-IMIDAZO[1,5-A][1,4]BENZODIAZEPINE-3-CARBOXYLIC ACID, 8-FLUORO-5,6-DIHYDRO-5-METHYL-6-OXO-, ETHYL ESTER;RO 15-1788;FlumazenilăFlumazepil;FlumazenilUsDmf |
CAS: | 78755-81-4 |
MF: | C15H14FN3O3 |
MW: | 303.29 |
EINECS: | |
Product Categories: | Active Pharmaceutical Ingredients;GABA/Glycine receptor;GABA;Amines;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;ZEBETA;Other APIs;antagonist;API |
Mol File: | 78755-81-4.mol |
Flumazenil Chemical Properties |
mp | 201-203°C |
storage temp. | 2-8°C |
form | solid |
color | white |
Water Solubility | 128 mg/L |
CAS DataBase Reference | 78755-81-4(CAS DataBase Reference) |
NIST Chemistry Reference | Flumazenil(78755-81-4) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-27-36/37/39 |
WGK Germany | 2 |
RTECS | NI2922170 |
MSDS Information |
Provider | Language |
---|---|
Flumazenil | English |
SigmaAldrich | English |
Flumazenil Usage And Synthesis |
Chemical Properties | Colourless crystals |
Usage | Imidazodiazepine which selectively blocks the central effects of classic benzodiazepines. It is used as benzodiazepine antagonist. |
Usage | beta-blocker, antihypertensive |
Usage | benzodiazepine antagonist sedation reversal drug |
Biological Activity | Benzodiazepine antagonist, non-selective for α 1, α 2, α 3 or α 5-containing GABA A receptors. Centrally active upon systemic administration in vivo . |
Flumazenil Preparation Products And Raw materials |
Raw materials | Hydrogen peroxide-->Ethyl cyanoacetate-->N,N-Dimethylaniline-->Anthranilic acid-->Sodium tert-butoxide-->Sarcosine-->6-Fluoroisatoic anhydride-->5-Fluoroisatin |