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Tel: +86-371- 86259723
Tel: 17734809689
Tel: 17734809689
Tel: 86-371-86259723
Tel: 17734809689
Tel: 17734809689
Mobile: 17734809689
Tel: +86-371- 86259723
Fax: +86-371- 86259723
Province/state: HENAN
City: ZHENGZHOU
Street: Mingmen International Center, NO.222 Dongming Road,Zhengzhou,Henan,China
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| Tris Base Basic information |
| Product Name: | Tris Base |
| Synonyms: | 1,1,1-tris(hydroxymethyl)-methanamin;1,1,1-tris(hydroxymethyl)-methylamin;1,1,1-tris(hydroxymethyl)methylamine;1,3-Propanediol,2-amino-2-(hydroxymethyl)-;2-amino-2-(hydroxymethyl)-3-propanediol;2-Amino-2-hydroxymethylpropanediol;2-Amino-2-methylol-1,3-propanediol;3-Propanediol,2-amino-2-(hydroxymethyl)-1 |
| CAS: | 77-86-1 |
| MF: | C4H11NO3 |
| MW: | 121.14 |
| EINECS: | 201-064-4 |
| Product Categories: | Biochemistry;Reagents for Electrophoresis;Buffer;ACS Grade Buffers;Amino Alcohols;Biological Buffers;Buffers A to Z;Building Blocks;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;API;Pharmaceutical intermediates;#N/A |
| Mol File: | 77-86-1.mol |
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| Tris Base Chemical Properties |
| mp | 167-172 °C(lit.) |
| bp | 219-220 °C10 mm Hg(lit.) |
| density | 1,353 g/cm3 |
| Fp | 219-220°C/10mm |
| storage temp. | 2-8°C |
| solubility | H2O: 4 M at 20 °C, clear, colorless |
| form | crystalline |
| color | white |
| Water Solubility | 550 g/L (25 ºC) |
| Sensitive | Hygroscopic |
| Merck | 14,9772 |
| BRN | 741883 |
| Stability: | Stable. Incompatible with bases, strong oxidizing agents. Protect from moisture. |
| CAS DataBase Reference | 77-86-1(CAS DataBase Reference) |
| NIST Chemistry Reference | 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-(77-86-1) |
| EPA Substance Registry System | 1,3-Propanediol, 2-amino-2-(hydroxymethyl)- (77-86-1) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-37/39-24/25-23 |
| WGK Germany | 2 |
| RTECS | TY2900000 |
| F | 3 |
| HazardClass | IRRITANT |
| HS Code | 29221980 |
| Hazardous Substances Data | 77-86-1(Hazardous Substances Data) |
| MSDS Information |
| Provider | Language |
|---|---|
| 2-Amino-2-(hydroxymethyl)-1,3-propanediol | English |
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| Tris Base Usage And Synthesis |
| Chemical Properties | White crystal or powder. Melting point 171-172℃, boiling point 219-220℃/1.3kPa, soluble in ethanol and water, slightly soluble in ethyl acetate, benzene, insoluble in ether, carbon tetrachloride,copper,aluminum corrosion effects,irritant. |
| Uses of Biology | Tris base, also known as THAM, is widely used as a biological buffer or as a component of buffer formulations such as TAE and TBE buffers. Tris has a pKa of 8.06 and is very useful in the biology and biochemistry lab because it has buffering capabilities in the range of the typical physiological pH of most living organisms (pH 7.0-9.0). Tris has been reported to interfere with the activity of a number of enzymes, it should therefore be used carefully when studying proteins. |
| Uses |
1, Tris buffer, only nucleic acids and proteins are widely used as solvents. 2, Tris is used for protein crystal growth under different pH conditions. 3, Tris buffer having a low ionic strength can be used nematode (C. elegans) is formed lamin (lamin) intermediate fibers. 4, Tris is a major component of protein electrophoresis buffer. 5, Tris for the preparation of a surfactant, a vulcanization accelerator, and some drug intermediates. 6, Tris titrated also used as standard. |
| Chemical Properties | White crystalline powder |
| Biological Activity | Commonly used laboratory reagent |
| Tris Base Preparation Products And Raw materials |
| Raw materials | Methanol-->Potassium carbonate-->Palladium-->Paraformaldehyde-->Nitromethane-->Tris(hydroxymethyl)nitromethane |