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1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Basic information
Product Name: 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Synonyms: 1-METHYL-4-1H-PYRAZOLEBORONIC ACID, PINACOL ESTER;1-METHYL-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-1H-PYRAZOLE;1-METHYL-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-PYRAZOLE;1-METHYL-1H-PYRAZOLE-4-BORONIC ACID PINACOL ESTER;1-METHYLPYRAZOLE-4-BORONIC ACID PINACOL ESTER;1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole, 97+%;1-Methyl-4-(4,4,5,5-Tetramethy;1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-
CAS: 761446-44-0
MF: C10H17BN2O2
MW: 208.07
EINECS:
Product Categories: Organoborons;Pyrazole;Boronic acid;Heterocyclic Building Blocks;Boronate Esters;Boronic Acids and Derivatives;Chemical Synthesis;Heteroaryl Boronate Esters;Organometallic Reagents
Mol File: 761446-44-0.mol
1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Chemical Properties
mp 59-64 °C(lit.)
storage temp. Refrigerator (+4°C)
CAS DataBase Reference 761446-44-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,F,Xi
Risk Statements 22-36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
Hazard Note Irritant/Flammable
HazardClass IRRITANT
MSDS Information
Provider Language
SigmaAldrich English
1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Usage And Synthesis
Chemical Properties White to light yellow crystal powde
Usage Reagent used for• ;Suzuki-Miyaura cross-coupling reactions1,2,3• ;Transesterification reactions4Reagent used for preparation of• ;Aminothiazoles as γ-secretase modulators5• ;Amino-pyrido-indol-carboxamides, as potential JAK2 inhibitors for myeloproliferative disorders therapy6• ;Pyridine derivatives as TGF-β1 and activin A signalling inhibitors7• ;MK-2461 analogs as inhibitors of c-Met kinase for the treatment of cancer8
Usage suzuki reaction
1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Preparation Products And Raw materials
Raw materials Tetrahydrofuran-->Potassium hydroxide -->n-Butyllithium-->Iodomethane-->Trimethyl borate-->Methyl bromide -->Pinacol-->MOLECULAR SIEVE-->4-Bromopyrazole
Details
1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Basic information
Product Name: 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Synonyms: 1-METHYL-4-1H-PYRAZOLEBORONIC ACID, PINACOL ESTER;1-METHYL-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-1H-PYRAZOLE;1-METHYL-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-PYRAZOLE;1-METHYL-1H-PYRAZOLE-4-BORONIC ACID PINACOL ESTER;1-METHYLPYRAZOLE-4-BORONIC ACID PINACOL ESTER;1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole, 97+%;1-Methyl-4-(4,4,5,5-Tetramethy;1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-
CAS: 761446-44-0
MF: C10H17BN2O2
MW: 208.07
EINECS:
Product Categories: Organoborons;Pyrazole;Boronic acid;Heterocyclic Building Blocks;Boronate Esters;Boronic Acids and Derivatives;Chemical Synthesis;Heteroaryl Boronate Esters;Organometallic Reagents
Mol File: 761446-44-0.mol
1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Chemical Properties
mp 59-64 °C(lit.)
storage temp. Refrigerator (+4°C)
CAS DataBase Reference 761446-44-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,F,Xi
Risk Statements 22-36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
Hazard Note Irritant/Flammable
HazardClass IRRITANT
MSDS Information
Provider Language
SigmaAldrich English
1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Usage And Synthesis
Chemical Properties White to light yellow crystal powde
Usage Reagent used for• ;Suzuki-Miyaura cross-coupling reactions1,2,3• ;Transesterification reactions4Reagent used for preparation of• ;Aminothiazoles as γ-secretase modulators5• ;Amino-pyrido-indol-carboxamides, as potential JAK2 inhibitors for myeloproliferative disorders therapy6• ;Pyridine derivatives as TGF-β1 and activin A signalling inhibitors7• ;MK-2461 analogs as inhibitors of c-Met kinase for the treatment of cancer8
Usage suzuki reaction
1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole Preparation Products And Raw materials
Raw materials Tetrahydrofuran-->Potassium hydroxide -->n-Butyllithium-->Iodomethane-->Trimethyl borate-->Methyl bromide -->Pinacol-->MOLECULAR SIEVE-->4-Bromopyrazole
China (Mainland)
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