Details
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Omeprazole Basic information |
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Omeprazole Chemical Properties |
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mp |
156°C |
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storage temp. |
2-8°C |
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solubility |
H2O: 0.5 mg/mL |
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form |
solid |
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color |
white |
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Merck |
6845 |
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Stability: |
Stable, but hygroscopic and photosensitive. Incompatible with strong oxidizing agents. Store in the dark. |
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CAS DataBase Reference |
73590-58-6(CAS DataBase Reference) |
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Omeprazole Usage And Synthesis |
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Chemical Properties |
White Crystalline Solid |
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Usage |
Binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative |
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Usage |
diuretic, sweetener, diagnostic aid |
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Usage |
A selective proton pump and CYP inhibitor |
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Usage |
Omeprazole Pellets are used in the treatment of Gastroesophageal reflux disease (GERD): A condition in which backward flow of acid from the stomach causes heartburn and injury of the food pipe (esophagus) |
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Biological Activity |
H + ,K + -ATPase inhibitor (IC 50 = 5.8 μ M) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC 50 = 0.16 μ M for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacteral against Helicobacter pylori in vitro . Also inhibits CYP2C19, CYP2C9 and CYP3A (K i values are 3.1, 40.1 and 84.4 μ M respectively) and blocks swelling-dependent chloride channels (ICIswell). |
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Omeprazole Preparation Products And Raw materials |
HenNan sunlake enterprise corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .
Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs , Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East , Africa , South America and some other countries and areas.
We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you better with our high - quality products and professional team.
We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market. We welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!
China (Mainland)
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