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Country: China (Mainland)
Business Type:Trading Company
Tel: +86-371- 86259723
Tel: 17734809689
Tel: 17734809689
Tel: 86-371-86259723
Tel: 17734809689
Tel: 17734809689
Mobile: 17734809689
Tel: +86-371- 86259723
Fax: +86-371- 86259723
Province/state: HENAN
City: ZHENGZHOU
Street: Mingmen International Center, NO.222 Dongming Road,Zhengzhou,Henan,China
MaxCard:
CAS NO.70-25-7
1.Certificate Of Analysis (COA)
2.Material Safety Data Sheet (MSDS)
3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)
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4. Mixed containers with different mixed items in one container
About Company
Product Name: | 1-Methyl-3-nitro-1-nitrosoguanidine |
Synonyms: | 1-METHYL-3-NITRO-1-NITROSOGUANIDINE;DIAZOMETHANE PRECURSOR;MNNG;N-METHYL-N'-NITRO-N-NITROSOGUANIDINE;N-METHYL-N-NITROSO-N'-NITROGUANIDINE;1-Methyl-1-Nitroso-3-nitroguanidine;1-methyl-3-nitro-1-nitroso-guanidin;1-nitroso-3-nitro-1-methylguanidine |
CAS: | 70-25-7 |
MF: | C2H5N5O3 |
MW: | 147.09 |
EINECS: | 200-730-1 |
Product Categories: | Diazomethane Precursors & Equivalents (GC Derivatizing Reagents);Analytical Chemistry;Esterification & Alkylation (GC Derivatizing Reagents);GC Derivatizing Reagents;Mutagenesis Research Chemicals |
Mol File: | 70-25-7.mol |
1-Methyl-3-nitro-1-nitrosoguanidine Chemical Properties |
mp | 118°C (dec.) |
storage temp. | 0-6°C |
Water Solubility | Reacts violently |
Merck | 6103 |
Stability: | Unstable. Reacts violently with water. May detonate under impact. Heat, light and moisture sensitive. May explode if stored in sealed ampules. Highly flammable. Incompatible with aqueous solutions, acids, bases, oxidizing agents, reducing agents. Alkaline hydrolysis releases toxic and explosive gases. |
CAS DataBase Reference | 70-25-7(CAS DataBase Reference) |
NIST Chemistry Reference | Guanidine, n-methyl-n'-nitro-n-nitroso-(70-25-7) |
EPA Substance Registry System | Guanidine, N-methyl-N'-nitro-N-nitroso- (70-25-7) |
Safety Information |
Hazard Codes | T;N,N,T |
Risk Statements | 45-20-36/38-51/53 |
Safety Statements | 53-45-61 |
RIDADR | 2926 |
RTECS | MF4200000 |
HazardClass | 4.1 |
PackingGroup | II |
Hazardous Substances Data | 70-25-7(Hazardous Substances Data) |
1-Methyl-3-nitro-1-nitrosoguanidine Usage And Synthesis |
Chemical Properties | yellow to pink crystals |
Usage | A DNA-damaging agent, used as a positive control in SHE cell transformation assays. |
General Description | A yellow powder. Melting point 244°F. Decomposes above 212°F. A suspected carcinogen. Extremely hazardous as a mutagen. Avoid skin contact and inhalation of of vapors. Usually stored frozen (below 32°F) in polyethylene bottles that are tightly closed and contained in a metal can. May decomposed during prolonged storage and develop sufficient pressure in a closed container to explode. Keep away from heat, sparks, and open flame. |
Air & Water Reactions | Highly flammable. Reacts violently with water . |
Reactivity Profile | 1-Methyl-3-nitro-1-nitrosoguanidine will detonate under high impact. 1-Methyl-3-nitro-1-nitrosoguanidine is sensitive to heat. A sample has exploded when melted in a sealed capillary tube. Incompatible with acids, bases, oxidizing agents and reducing agents. Reacts with bases to release highly toxic, irritating and explosive gases. Reacts slowly with acids to release nitrous acid. Reacts with various nucleophiles, especially amines and thiols. Reacts with aqueous potassium hydroxide to form a highly reactive compound. The crude product from aqueous nitrosation is pyrophoric but recrystallized material is stable . |
Health Hazard | Fire may produce irritating and/or toxic gases. Contact may cause burns to skin and eyes. Contact with molten substance may cause severe burns to skin and eyes. Runoff from fire control may cause pollution. |
Fire Hazard | Flammable/combustible material. May be ignited by friction, heat, sparks or flames. Some may burn rapidly with flare burning effect. Powders, dusts, shavings, borings, turnings or cuttings may explode or burn with explosive violence. Substance may be transported in a molten form at a temperature that may be above its flash point. May re-ignite after fire is extinguished. |
1-Methyl-3-nitro-1-nitrosoguanidine Preparation Products And Raw materials |
Raw materials | Etanol-->Methanol-->Sulfuric acid -->Nitric acid-->Sodium nitrite-->1-Butanol-->METHYLAMINE-->2-Methyl-2-thiopseudourea sulfate-->Cyanamide-->Nitroguanidine-->1-Methyl-3-nitroguanidine |