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CAS NO.69-57-8
1(10-100)Metric Ton1(10-100)Metric Ton
| Penicillin G sodium salt Basic information |
| Product Name: | Penicillin G sodium salt |
| Synonyms: | 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-,monosodiumsalt;5alpha,6beta)]-nylacetyl)amino]-[2s-(2alphmonosodiumsalt;americanpenicillin;benzylpenicillinicacidsodiumsalt;crystapen;mycofarm;novocillin;pen-a-brasive |
| CAS: | 69-57-8 |
| MF: | C16H17N2NaO4S |
| MW: | 356.37 |
| EINECS: | 200-710-2 |
| Product Categories: | Antibiotics for Research and Experimental Use;beta-Lactams (Antibiotics for Research and Experimental Use);Biochemistry;API;PENTIDS;antibiotic;Pharmaceutical raw chemicals |
| Mol File: | 69-57-8.mol |
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| Penicillin G sodium salt Chemical Properties |
| mp | 209-212°C |
| density | 1.41 |
| refractive index | 300 ° (C=2, H2O) |
| storage temp. | 2-8°C |
| solubility | H2O: 100 mg/mL Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for extended periods. Solutions are stable at 37°C for 3 days. |
| form | powder |
| Water Solubility | 5-10 g/100 mL at 25 ºC |
| Merck | 7094 |
| Stability: | Stability Stable, but incompatible with a wide variety of materials, including acids, oxidizing agents, heavy metals, alcohols, glycerol, thiomersal, many surface-active agents, alkalies, peroxides, reducing agents, lanolin, glycol, sugars, amines, iodine, iodides, thiols. Hygroscopic. |
| CAS DataBase Reference | 69-57-8(CAS DataBase Reference) |
| EPA Substance Registry System | 4-Thia-1-azabicyclo[ 3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl) amino]-(2S,5R,6R)-, monosodium salt(69-57-8) |
| Safety Information |
| Hazard Codes | Xn,Xi |
| Risk Statements | 42/43 |
| Safety Statements | 22-36/37-45 |
| WGK Germany | 2 |
| RTECS | XH9800000 |
| F | 10-23 |
| HS Code | 29411000 |
| MSDS Information |
| Provider | Language |
|---|---|
| 3,3-Dimethyl-7-oxo-6-(2-phenyl-acetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid monosodium salt | English |
| SigmaAldrich | English |
| Penicillin G sodium salt Usage And Synthesis |
| Chemical Properties | White powder |
| Usage | Sodium salt of Penicillin G, an antibacterial, antimicrobial medication. Used in the treatment of pneumococcus and streptococcus bacterial infections. |
| General Description | White to slightly yellow crystalline powder with a faint odor. pH (10% solution) 5.5-7.5. |
| Air & Water Reactions | Water soluble. |
| Reactivity Profile | Penicillin G sodium salt is hygroscopic. Penicillin G sodium salt is incompatible with acids, oxidizing agents (especially in the presence of trace metals), heavy metal ions such as copper, lead, zinc and mercury; glycerol, sympathomimetic amines, thiomersal, wood alcohols, cetostearyl alcohol, hard paraffins, macrogols, cocoa butter and many ionic an nonionic surface-active agents. Penicillin G sodium salt is also incompatible with alkalis, compounds leached from vulcanized rubber, hydrochlorides of tetracyclines and organic peroxides. Other incompatibilities include reducing agents, alcohols, other hydroxy compounds, self-emulsifying stearyl alcohol, emulsifying wax, lanolin, crude cholinesterated bases, glycol, sugars, amines, aminacrine hydrochloride, ephedrine, procaine, rubber tubing, thiamine hydrochloride, zinc oxide, oxidized cellulose, iodine, iodides, thiols, chlorocresol and resorcinol. Penicillin G sodium salt may also be incompatible with naphthalene oils and vitamin B. |
| Fire Hazard | Flash point data for Penicillin G sodium salt are not available; however, Penicillin G sodium salt is probably combustible. |
| Penicillin G sodium salt Preparation Products And Raw materials |
| Raw materials | Etanol-->Sodium hydroxide-->Ethyl acetate-->Sodium sulfate-->1-Butanol-->Sodium acetate-->D(+)-Glucose-->Ammonium sulfate-->Phenylacetic acid-->Butyl acetate-->Potassium benzylpenicillin |
| Preparation Products | Ticarcillin disodium salt |
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