HENAN SUNLAKE ENTERPRISE CORPORATION
Free supplier Enterprise Certification
- Free
supplier - 9th
years
Free supplier Enterprise Certification
Product Certification&
Enterprise Certification
Country: 
China (Mainland)
Business Type:Trading Company
Tel: +86-371- 86259723
Tel: 17734809689
Tel: 17734809689
Tel: 86-371-86259723
Tel: 17734809689
Tel: 17734809689
Mobile: 17734809689
Tel: +86-371- 86259723
Fax: +86-371- 86259723
Province/state: HENAN
City: ZHENGZHOU
Street: Mingmen International Center, NO.222 Dongming Road,Zhengzhou,Henan,China
MaxCard:
Contact Suppliers
CAS NO.68844-77-9
| Astemizole Basic information |
| Product Name: | Astemizole |
| Synonyms: | 1-((4-fluorophenyl)methyl)-n-(1-(2-(4-methoxyphenyl)ethyl)-4-piperidinyl)-1h-b;1-(p-fluorobenzyl)-2-((1-(2-(p-methoxyphenyl)ethyl)piperid-4-yl)amino)benzim;1-(p-fluorobenzyl)-2-((1-(p-methoxyphenethyl)-4-piperidyl)amino)benzimidazole;1h-benzimidazol-2-amine,1-((4-fluorophenyl)methyl)-n-(1-(2-(4-methoxyphenyl)et;astemison;astemizol;astemizol(inn-spanish);astemizolum(inn-latin) |
| CAS: | 68844-77-9 |
| MF: | C28H31FN4O |
| MW: | 458.57 |
| EINECS: | 272-441-9 |
| Product Categories: | Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Histamine receptor;Amines;ASCABIOL |
| Mol File: | 68844-77-9.mol |
|
|
|
| Astemizole Chemical Properties |
| Melting point | 172.9°C |
| storage temp. | Store at +4°C |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| RTECS | DD8968000 |
| Hazardous Substances Data | 68844-77-9(Hazardous Substances Data) |
| Astemizole Usage And Synthesis |
| Chemical Properties | Crystalline Solid |
| Usage | Nonsedating-type histamine H1-receptor antagonist. Potential for combination therapy with antivancer drugs such as doxorubicin in resistant leukemia. Antihistaminic |
| Usage | scabicide |
| Biological Activity | Orally active, potent histamine H 1 antagonist (IC 50 = 4 nM) that displays 20-fold, > 250-fold and > 250-fold selectivity over 5-HT, dopamine and muscarinic acetylcholine receptors respectively. Exhibits antimalarial activity in multidrug resistant strains in vitro (IC 50 = 227 - 734 nM). Also potent hERG K + channel blocker (IC 50 = 0.9 nM) that displays cardiotoxicity in vivo . |
| Astemizole Preparation Products And Raw materials |
| Raw materials | Iodomethane-->Bromoethane-->1,4-Dimethoxybenzene |
We have clients throughout the world：
Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet your desire.
Our Laboratoy
We have our own independent lab test center：
This makes sure that our technology support is reliable and authoritative.All of self-owned fine chemicals are manufactured strictly in accordance with international standard.,and also has scientific cooperation with local colleges and institutes.
Our factory
High quality with competitive price：
We are manufacturer and can provide high quality products with factory price
Package & Shipment
Fast and safe delivery：
Parcels can be sent out within 24 hours after payment. Tracking number is available
Secure and discreet shipment. You have various choices of transportation methods
