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Tel: 86-371-86259723
Tel: 17734809689
Tel: 17734809689
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Tel: +86-371- 86259723
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CAS NO.67-68-5
1.Certificate Of Analysis (COA)
2.Material Safety Data Sheet (MSDS)
3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)
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About Company
| Product Name: | Dimethyl sulfoxide |
| Synonyms: | (CH3)2SO;A 10846;a10846;Decap;Deltan;Demasorb;Demavet;Demeso |
| CAS: | 67-68-5 |
| MF: | C2H6OS |
| MW: | 78.13 |
| EINECS: | 200-664-3 |
| Mol File: | 67-68-5.mol |
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| Dimethyl sulfoxide Chemical Properties |
| mp | 18.4 °C |
| bp | 189 °C(lit.) |
| density | 1.100 g/mL at 20 °C |
| vapor density | 2.7 (vs air) |
| vapor pressure | 0.42 mm Hg ( 20 °C) |
| FEMA | 3875 |
| refractive index |
n |
| Fp | 192 °F |
| storage temp. | Store at RT. |
| form | liquid (temperature dependent) |
| color | clear colorless |
| FreezingPoint | 18.4℃ |
| Sensitive | Hygroscopic |
| Merck | 14,3259 |
| BRN | 506008 |
| Stability: | Stable. Incompatible with a very wide range of materials, including acid chlorides, strong acids, strong oxidizing agents, strong reducing agents, phosphorus halides, moisture, copper wool + trichloroacetic acid. Reacts violently with a number of materials - consult a full data sheet before use. Hygroscopic. |
| CAS DataBase Reference | 67-68-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Dimethyl sulfoxide(67-68-5) |
| EPA Substance Registry System | Methane, sulfinylbis-(67-68-5) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 24/25-37/39-26-36-23 |
| WGK Germany | 1 |
| RTECS | PV6210000 |
| F | 3 |
| HS Code | 29309070 |
| Hazardous Substances Data | 67-68-5(Hazardous Substances Data) |
| Chemical Properties | colourless liquid |
| Usage | DMSO is a polar aprotic solvent used in chemical reactions, in polymerase chain reactions (PCR) and as a cryoprotectant vitrification agent for the preservation of cells, tissues and organs. DMSO is used in cell freezing media to protect cells from ice crystal induced mechanical injury. It is used for frozen storage of primary, sub-cultured, and recombinant heteroploid and hybridoma cell lines; embryonic stem cells (ESC), and hematopoietic stem cells. DMSO is frequently used in the combinations with BSA or fetal bovine serum (FBS). |
| Usage | Human and animal cell lines grown in culture are generally stored frozen. Freezing protects the cell line from changes due to genetic drift and minimizes risk of contamination. Liquid nitrogen used in conjunction with a cryoprotective agent such as DMSO is a widely used method for preserving cells. Without the presence of a cryoprotective agent, freezing is lethal to most mammalian cells. Damage is caused by mechanical injury by ice crystals, concentration of electrolytes, pH changes, and denaturation of proteins. These lethal effects are minimized by adding a cryoprotective agent which lowers |
| Usage | Dimethyl sulfoxide (1-10%) has been shown to accelerate strand renaturation and is believed to give the nucleic acid thermal stability against depurination. As a PCR cosolvent, DMSO may help improve yields, especially in long PCR. |
| Usage | A polar aprotic solvent used in polymerase chain reactions (PCR) and as a cryoprotectant vitrification agent for the preservation of cells, tissues and organs. |
| Usage | Suitable for HPLC, spectrophotometry, environmental testing |
| General Description | A clear liquid, essentially odorless. Closed cup flash point 192°F. Vapors are heavier than air. Contact with the skin may cause stinging and burning and lead to an odor of garlic on the breath. An excellent solvent that can transport toxic solutes through the skin. High vapor concentrations may cause headache, dizziness, and sedation. |
| Air & Water Reactions | Denser than water and miscible in water. |
| Reactivity Profile | Dimethyl sulfoxide decomposes violently on contact with many acyl halides, aryl halides and related compounds such as phenyl and tolyl chloride, acetyl chloride, benzenesulfonyl chloride, benzoyl chloride, cyanuric chloride, phosphorus chloride, phosphorus oxychloride, and thionyl chloride [Chem. Eng. News 35(9):87 (1957)]. Reacts, possibly violently, with iodine pentafluoride [Chem. Eng. News 47(12):, 109(1969)]. Vacuum distillation from anhydrous magnesium perchlorate led to an explosion [MCA Case History 1187(1966)]. Violently reactive with fluorinating agents such as silver fluoride [Chem. Eng. News 44(24):7(1956)]. Can explode with sodium hydride [Chem. Eng. News 44(24):7(1966)]. Mixture with methyl bromide resulted in an explosion that shattered the apparatus [NFPA 491M, 1991]. Forms salts with perchloric acid that are explosive when dry [Chem. Abst. 44:p3935d (1950)]. Decomposes when heated above normal boiling point. |
| Health Hazard | Slight eye irritation. |
| Fire Hazard | Special Hazards of Combustion Products: Sulfur dioxide, formaldehyde, and methyl mercaptan can form |
| Biological Activity | Solvent with wide ranging applications in biological research. |
| Dimethyl sulfoxide Preparation Products And Raw materials |