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CAS NO.67-20-9
Nitrofurantoin Basic information |
Product Name: | Nitrofurantoin |
Synonyms: | 1-(((5-nitro-2-furanyl)methylene)amino)-2,4-imidazolidinedione;1-(5-NITRO-2-FURFURYLIDENEAMINO)HYDANTOIN;1-[(5-nitrofurfurylidene)amino]hydantoin;LABOTEST-BB LT00134625;FURADOXYL;N-(5-NITRO-2-FURFURYLIDENE)-1-AMINOHYDANTOIN;NITROFURANTOIN;NITROFURANTOINE |
CAS: | 67-20-9 |
MF: | C8H6N4O5 |
MW: | 238.16 |
EINECS: | 200-646-5 |
Product Categories: | Furan&Benzofuran;Peptide Synthesis/Antibiotics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate;antibiotic |
Mol File: | 67-20-9.mol |
Nitrofurantoin Chemical Properties |
mp | 268°C |
storage temp. | 0-6°C |
form | crystalline |
color | yellow |
Water Solubility | <0.01 g/100 mL at 19 ºC |
Merck | 13,6632 |
Stability: | Stability Stable, but light-sensitive. Combustible. Incompatible with strong oxidizing agents, strong alkalies, strong acids. Decomposes upon contact with most metals other than stainless steel and aluminium. |
CAS DataBase Reference | 67-20-9(CAS DataBase Reference) |
NIST Chemistry Reference | Hydantoin, n-(5-nitro-2-furfurylidene)-1-amino-(67-20-9) |
EPA Substance Registry System | 2,4-Imidazolidinedione, 1-[[(5-nitro-2-furanyl)methylene] amino]-(67-20-9) |
Safety Information |
Hazard Codes | Xn |
Risk Statements | 22-42/43 |
Safety Statements | 22-36/37-45 |
RIDADR | 2811 |
WGK Germany | 3 |
RTECS | MU2800000 |
HazardClass | 6.1(b) |
PackingGroup | III |
HS Code | 29349990 |
Hazardous Substances Data | 67-20-9(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
Nitrofurantoin | English |
SigmaAldrich | English |
ALFA | English |
Nitrofurantoin Usage And Synthesis |
Chemical Properties | lemon yellow crystalline powder |
Usage | counterirritant |
Usage | A nitrofuran antibiotic with low resistance potential that is rapidly metabolized by mammals. Active against both Gram-positive and Gram-negative bacteria. Nitrofurantoin is also a prooxidant that is cytotoxic due to the generation of intracellular H2O2. Antibacterial. |
General Description | Odorless lemon yellow crystals or fine yellow powder. Bitter taste. |
Air & Water Reactions | Insoluble in water. |
Reactivity Profile | Nitrofurantoin is sensitive to light. Nitrofurantoin is incompatible with alkalis. Nitrofurantoin is also incompatible with strong oxidizers and strong acids. Nitrofurantoin decomposes on contact with metals other than stainless steel and aluminum. |
Fire Hazard | Flash point data for Nitrofurantoin are not available; however, Nitrofurantoin is probably combustible. |
Nitrofurantoin Preparation Products And Raw materials |
Raw materials | Acetone-->Hydrazinium hydroxide-->Ethyl chloroacetate-->Furfural-->Semicarbazide-->5-Nitro-2-furaldehyde diacetate |
Nitrofurantoin Basic information |
Product Name: | Nitrofurantoin |
Synonyms: | 1-(((5-nitro-2-furanyl)methylene)amino)-2,4-imidazolidinedione;1-(5-NITRO-2-FURFURYLIDENEAMINO)HYDANTOIN;1-[(5-nitrofurfurylidene)amino]hydantoin;LABOTEST-BB LT00134625;FURADOXYL;N-(5-NITRO-2-FURFURYLIDENE)-1-AMINOHYDANTOIN;NITROFURANTOIN;NITROFURANTOINE |
CAS: | 67-20-9 |
MF: | C8H6N4O5 |
MW: | 238.16 |
EINECS: | 200-646-5 |
Product Categories: | Furan&Benzofuran;Peptide Synthesis/Antibiotics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate;antibiotic |
Mol File: | 67-20-9.mol |
Nitrofurantoin Chemical Properties |
mp | 268°C |
storage temp. | 0-6°C |
form | crystalline |
color | yellow |
Water Solubility | <0.01 g/100 mL at 19 ºC |
Merck | 13,6632 |
Stability: | Stability Stable, but light-sensitive. Combustible. Incompatible with strong oxidizing agents, strong alkalies, strong acids. Decomposes upon contact with most metals other than stainless steel and aluminium. |
CAS DataBase Reference | 67-20-9(CAS DataBase Reference) |
NIST Chemistry Reference | Hydantoin, n-(5-nitro-2-furfurylidene)-1-amino-(67-20-9) |
EPA Substance Registry System | 2,4-Imidazolidinedione, 1-[[(5-nitro-2-furanyl)methylene] amino]-(67-20-9) |
Safety Information |
Hazard Codes | Xn |
Risk Statements | 22-42/43 |
Safety Statements | 22-36/37-45 |
RIDADR | 2811 |
WGK Germany | 3 |
RTECS | MU2800000 |
HazardClass | 6.1(b) |
PackingGroup | III |
HS Code | 29349990 |
Hazardous Substances Data | 67-20-9(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
Nitrofurantoin | English |
SigmaAldrich | English |
ALFA | English |
Nitrofurantoin Usage And Synthesis |
Chemical Properties | lemon yellow crystalline powder |
Usage | counterirritant |
Usage | A nitrofuran antibiotic with low resistance potential that is rapidly metabolized by mammals. Active against both Gram-positive and Gram-negative bacteria. Nitrofurantoin is also a prooxidant that is cytotoxic due to the generation of intracellular H2O2. Antibacterial. |
General Description | Odorless lemon yellow crystals or fine yellow powder. Bitter taste. |
Air & Water Reactions | Insoluble in water. |
Reactivity Profile | Nitrofurantoin is sensitive to light. Nitrofurantoin is incompatible with alkalis. Nitrofurantoin is also incompatible with strong oxidizers and strong acids. Nitrofurantoin decomposes on contact with metals other than stainless steel and aluminum. |
Fire Hazard | Flash point data for Nitrofurantoin are not available; however, Nitrofurantoin is probably combustible. |
Nitrofurantoin Preparation Products And Raw materials |
Raw materials | Acetone-->Hydrazinium hydroxide-->Ethyl chloroacetate-->Furfural-->Semicarbazide-->5-Nitro-2-furaldehyde diacetate |