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HENAN SUNLAKE ENTERPRISE CORPORATION

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JW55

CAS NO.664993-53-7

  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,Other
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Product Details

Keywords

  • JW55
  • 664993-53-7
  • C25H26N2O5

Quick Details

  • ProName: JW55
  • CasNo: 664993-53-7
  • Molecular Formula: C25H26N2O5
  • Appearance: powder
  • Application: 664993-53-7
  • DeliveryTime: within 3-7 days
  • PackAge: as requested
  • Port: China Main Port
  • ProductionCapacity: 300 Kilogram/Month
  • Purity: 98%
  • Storage: store in cool, dry place
  • Transportation: by sea or by air
  • LimitNum: 1 Kilogram

Superiority

JW55 Basic information
Product Name: JW55
Synonyms: JW55;N-(4-((4-(4-Methoxyphenyl)tetrahydro-2H-pyran-4-yl)MethylcarbaMoyl)phenyl)furan-2-carboxaMide;N-[4-[[[[Tetrahydro-4-(4-methoxyphenyl)-2H-pyran-4-yl]methyl]amino]carbonyl]phenyl]-2-furancarboxamide;JW55 N-[4-[[[[Tetrahydro-4-(4-methoxyphenyl)-2H-pyran-4-yl]methyl]amino]carbonyl]phenyl]-2-furancarboxamide;JW 55, >=98%
CAS: 664993-53-7
MF: C25H26N2O5
MW: 434.48434
EINECS: -0
Product Categories: Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Inhibitors
Mol File: 664993-53-7.mol
JW55 Structure
 
JW55 Chemical Properties
storage temp.  2-8°C
 
Safety Information
MSDS Information
 
 
JW55 Usage And Synthesis
Usage JW-55 is an inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2). Activity results in stabilization of Axin2 and increased degradation of β-catenin. JW-55 inhibits the β-catenin signaling pathway. Also shown to decrease canonical Wnt signaling in SW480 and HCT-15 colon carcinoma cell lines. JW-55 reduces cell cycle progression and proliferation in SW480 cells in vitro.
 
JW55 Preparation Products And Raw materials

 

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