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CAS NO.656247-17-5
| Intedanib Basic information |
| Product Name: | Intedanib |
| Synonyms: | Intedanib;Vargatef;Nintedanib;Nintedanib (BIBF 1120);Nintedanib/Intedanib/Vargatef;Intedanib Vargatef;methyl (3Z)-3-[[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylate Nintedanib (BIBF 1120);Vargatef (nintedanib) |
| CAS: | 656247-17-5 |
| MF: | C31H33N5O4 |
| MW: | 539.62482 |
| EINECS: | |
| Product Categories: | Amines;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Inhibitors |
| Mol File: | 656247-17-5.mol |
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| Intedanib Chemical Properties |
| Safety Information |
| Intedanib Usage And Synthesis |
| Usage | It is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases; an indolinone as triple angiokinase inhibitors. |
| Usage | BIBF1120 (Vargatef) is a potent inhibitor of VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively |
| Intedanib Basic information |
| Product Name: | Intedanib |
| Synonyms: | Intedanib;Vargatef;Nintedanib;Nintedanib (BIBF 1120);Nintedanib/Intedanib/Vargatef;Intedanib Vargatef;methyl (3Z)-3-[[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylate Nintedanib (BIBF 1120);Vargatef (nintedanib) |
| CAS: | 656247-17-5 |
| MF: | C31H33N5O4 |
| MW: | 539.62482 |
| EINECS: | |
| Product Categories: | Amines;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Inhibitors |
| Mol File: | 656247-17-5.mol |
|
|
|
| Intedanib Chemical Properties |
| Safety Information |
| Intedanib Usage And Synthesis |
| Usage | It is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases; an indolinone as triple angiokinase inhibitors. |
| Usage | BIBF1120 (Vargatef) is a potent inhibitor of VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively |