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CAS:65141-46-0 C8H9N3O4 Nicorandil

CAS NO.65141-46-0

  • Min.Order: 100 Gram
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Product Details

Keywords

  • CAS:65141-46-0 C8H9N3O4 Nicorandil
  • CAS:65141-46-0 C8H9N3O4 Nicorandil
  • CAS:65141-46-0 C8H9N3O4 Nicorandil

Quick Details

  • ProName: CAS:65141-46-0 C8H9N3O4 Nicorandil
  • CasNo: 65141-46-0
  • Molecular Formula: C8H9N3O4
  • Appearance: white poweder
  • Application: CAS:65141-46-0 C8H9N3O4 Nicorandil
  • DeliveryTime: 5 working days after cash deposit
  • PackAge: Plastic vacuum packaging bag or bucket
  • Port: depend on clients require
  • ProductionCapacity: 1 Metric Ton/Day
  • Purity: 99%
  • Storage: under the cool and dry area
  • Transportation: by express or by sea
  • LimitNum: 100 Gram
  • Grade: Industrial Grade,Food Grade,Electron G...

Superiority

Nicorandil Basic information
Product Name: Nicorandil
Synonyms: n-[2-(nitroxy)ethyl]-3-pyridinecarboxamide;N-[2-(NITROOXY)ETHYL]-3-PYRIDINECARBOXAMIDE;NICORANDIL;PERISALOL;SIGMART;IKOREL;ADANCOR;2-nicotinamidoethylnitrate
CAS: 65141-46-0
MF: C8H9N3O4
MW: 211.17
EINECS: 265-514-1
Product Categories: Pharmaceutical;Intermediates & Fine Chemicals;Pharmaceuticals;Potassium channel;Aromatics;Heterocycles;Ikorel;reagent;Cardiovascular APIs
Mol File: 65141-46-0.mol
Nicorandil Structure
 
Nicorandil Chemical Properties
mp  92°C
storage temp.  Desiccate at +4°C
 
Safety Information
Hazard Codes  Xn
Risk Statements  22-41
Safety Statements  26-39
MSDS Information
 
 
Nicorandil Usage And Synthesis
Chemical Properties White solid
Usage An antianginal
Usage Antihypertensor
Biological Activity K ATP channel opener and NO donor, clinically used as antianginal agent. Preferentially activates SUR2B- versus SUR2A-containing K ATP channels (EC 50 values are 10 and > 500 mM respectively) and causes 1.6-fold increase in cardiac eNOS expression. Displays coronary and peripheral vasodilatory properties, reduces both pre- and after-load, and increases coronary blood flow. Also displays cardioprotective effects, possibly through ischemic preconditioning.
 
Nicorandil Preparation Products And Raw materials
Raw materials Nitric acid-->Ethanolamine-->2-N-BUTOXYETHYL METHACRYLATE-->Methyl nicotinate-->NICOTINOYL CHLORIDE HYDROCHLORIDE

 

Details

Products Name:

Nicorandil

Structural Formula:

Nicorandil

Chemical Name:

 

Molecular Formula :

C8H9N3O4

Molecular weight:

211．18

CAS No.:

65141-46-0

Specifications:

BP/EP/USP/CP

Use:

White to whitish needle crystal powder, antianginal drugs

 

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