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Tel: 17734809689
Tel: 86-371-86259723
Tel: 17734809689
Tel: 17734809689
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Tel: +86-371- 86259723
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CAS NO.64-73-3
1(10-100)Metric Ton1(10-100)Metric Ton
| Demeclocycline hydrochloride Basic information |
| Product Name: | Demeclocycline hydrochloride |
| Synonyms: | 7-chloro-4-dimethylamino-3,6,10,12,12a-pentahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxamide hydrochloride;7-CHLORO-6-DEMETHYLTETRACYCLINE HYDROCHLORIDE;DEMECLOCYCLINE;DEMECLOCYCLINE HYDROCHLORIDE;6,10,12,12a-pentahydroxy-1,11-dioxo-ydro-monohydrochloride;declomycinhydrochloride;demethylchlorotetracyclinehydrochloride;demethylchlortetracyclinehydrochloride |
| CAS: | 64-73-3 |
| MF: | C21H21ClN2O8.ClH |
| MW: | 501.32 |
| EINECS: | 200-592-2 |
| Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Amines;Chiral Reagents;API |
| Mol File: | 64-73-3.mol |
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| Demeclocycline hydrochloride Chemical Properties |
| mp | >245°C (dec.) |
| storage temp. | −20°C |
| solubility | H2O: 20 mg/mL, clear, very deep greenish yellow |
| form | powder |
| Merck | 13,2905 |
| CAS DataBase Reference | 64-73-3(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 43 |
| Safety Statements | 36/37 |
| WGK Germany | 2 |
| RTECS | QI7700000 |
| F | 8-10-21 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| Demeclocycline hydrochloride Usage And Synthesis |
| Chemical Properties | Yellow Solid |
| Usage | Antibacterial;Ribosomal protein synthesis inhibitor |
| Usage | Demeclocycline hydrochloride is a salt prepared from demeclocycline taking advantage of the basic dimethylamino group which protonates and readily forms a salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, demeclocycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis. |
| Usage | An antibiotic related to tetracycline and produced by streptomyces aureofaciens. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time |
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