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CAS NO.608-07-1
| 5-Methoxytryptamine Basic information |
| Product Name: | 5-Methoxytryptamine |
| Synonyms: | TIMTEC-BB SBB003309;RARECHEM AL BW 2333;O-METHYLSEROTONIN;O-METHYLSEROTONIN HYDROCHLORIDE;5-METHOXYTRYPTAMINE;5-METHOXYTRYPTAMINE HCL;AKOS JY2083095;AKOS B028531 |
| CAS: | 608-07-1 |
| MF: | C11H14N2O |
| MW: | 190.24 |
| EINECS: | 200-637-6 |
| Product Categories: | Indole/indoline/oxindole;Indole and Indoline;PHARMACEUTICAL INTERMEDIATES;Tryptamines;pharmacetical;Indoline & Oxindole;Indoles;Building Blocks;Heterocyclic Building Blocks;Non-Chiral heterocyclic compounds;Agonists;Amines;Heterocycles;Indole Derivatives;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals;Bioactive Small Molecules;Building Blocks;C11;Cell Biology;Chemical Synthesis;Heterocyclic Building Blocks;M |
| Mol File: | 608-07-1.mol |
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| 5-Methoxytryptamine Chemical Properties |
| mp | 245-250 °C (dec.)(lit.) |
| storage temp. | 2-8°C |
| form | crystalline |
| color | white |
| Merck | 13,6032 |
| CAS DataBase Reference | 608-07-1(CAS DataBase Reference) |
| NIST Chemistry Reference | 5-Methoxytryptamine(608-07-1) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38-20/21/22 |
| Safety Statements | 36-26 |
| WGK Germany | 3 |
| RTECS | NL4110000 |
| F | 8 |
| MSDS Information |
| Provider | Language |
|---|---|
| 5-Methoxytryptamine | English |
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| 5-Methoxytryptamine Usage And Synthesis |
| Chemical Properties | White to tan crystalline powder |
| Usage | A tryptamine derivative that is closely related to the neurotransmitter Melatonin (M215000) and Serotonin (S274980). It acts as a full agonist at the 5-HT1, 5-HT2, 5-HT4, 5-HT6, and 5-HT7 receptors but has no affinity for the 5-HT3 receptor. |
| Usage | Reactant for preparation of:• ;Carboline disaccharide domain of shishijimicin A1• ;Melatonin analogs for the reduction of intraocular pressure2• ;5-HT4 receptor ligands3• ;inhibitors of sortase A and isocitrate lyase4• ;Therapeutic agents for treatment of ischemia/reperfusion (I/R) injury5• ;Aurora and epidermal growth factor receptor kinase inhibitors6• ;Agents for the treatment of human papillomavirus infection7• ;Manzamine analogues for the control of neuroinflammation and cerebral infections8• ;Inhibitors of pro-inflammatory cytokines9& |
| Usage | 5HT agonist |
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Melatonin intermediate: |
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Standard |
Typical measured values |
|
Identification |
IR, NMR |
pass |
|
Appearance |
White crystals or crystalline powder |
pass |
|
Assay (TLC) |
≥99 |
≥ 99 |
|
Water |
≤0.5% |
0.12% |
|
Residue on ignition |
≤0.5% |
0.08% |
|
Heavy metal |
≤10ppm |
≤10ppm |
|
As |
≤2ppm |
≤10ppm |
|
Packaging |
25KG/drum |
|
