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HENAN SUNLAKE ENTERPRISE CORPORATION

Country: China (Mainland)

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Cyclophosphamide monohydrate

CAS NO.6055-19-2

  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,
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Product Details

Keywords

  • (bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide
  • 1-bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridinemonohydrate
  • 2-(bis(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphocyclohexane2-oxidemonohydr

Quick Details

  • ProName: Cyclophosphamide monohydrate
  • CasNo: 6055-19-2
  • Molecular Formula: C7H17Cl2N2O3P
  • Appearance: White to Off-White Solid
  • Application: 6055-19-2
  • DeliveryTime: 7-10 days after payment
  • PackAge: As required
  • Port: Shanghai/Tianjin/Qingdao
  • ProductionCapacity: 100-200 Kilogram/Month
  • Purity: 99%
  • Storage: 2-8°C
  • Transportation: By air/sea/express
  • LimitNum: 1 Kilogram
  • Grade: Pharma Grade

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About Certificate

 

1.Certificate Of Analysis (COA)
2.Material Safety Data Sheet (MSDS)
3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)

 

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About Company

 
HenNan sunlake enterprise corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .
     Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs ,  Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East ,  Africa , South America and some other countries and areas.
    We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you  better with our high - quality products and professional team.
    We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.
     We  welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!

Details

Product Name: Cyclophosphamide monohydrate
Synonyms: (bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide;1-bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridinemonohydrate;2-(bis(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphocyclohexane2-oxidemonohydr;2-(di(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphacyclohexane-2-oxidemonohydra;2h-1,3,2-oxazaphosphorine,tetrahydro-2-(bis(2-chloroethyl)amino)-,2-oxide,mo;-2monohydrate;cyclicn’,o-propyleneesterofn,n-bis(2-chloroethyl)phosphorodiamidicacidm;endoxanmonohydrate
CAS: 6055-19-2
MF: C7H17Cl2N2O3P
MW: 279.1
EINECS: 200-015-4
Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Intermediates & Fine Chemicals;Pharmaceuticals;Phosphorylating and Phosphitylating Agents;CYTOXAN;Anti-cancer&immunity
Mol File: 6055-19-2.mol
Cyclophosphamide monohydrate Structure
 
Cyclophosphamide monohydrate Chemical Properties
mp  49-51 °C(lit.)
Fp  >230 °F
storage temp.  2-8°C
solubility  H2O: 0.1 g/mL, clear, colorless
Water Solubility  40 g/L
Merck  14,2747
BRN  8167897
CAS DataBase Reference 6055-19-2(CAS DataBase Reference)
EPA Substance Registry System 2H-1,3,2-Oxazaphosphorin- 2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, monohydrate(6055-19-2)
 
Safety Information
Hazard Codes  T
Risk Statements  45-25-61-46-36/37/38-23/24/25
Safety Statements  53-45-37/39-26
RIDADR  UN 3464 6.1/PG 3
WGK Germany  3
RTECS  RP6157750
F  10
HazardClass  6.1
PackingGroup  II
MSDS Information
 
Cyclophosphamide monohydrate Usage And Synthesis
Chemical Properties White to Off-White Solid
Usage It is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. This substance is listed as a known human carcinogen.
Usage antineoplastic, alkylating agent
Usage alkylating agent in cancer therapy
General Description Fine white crystalline powder with a slightly bitter taste. Little or no odor.
Air & Water Reactions Water soluble. Sensitive to moisture and light. Aqueous solutions may be kept for a few hours above room temperature, but hydrolysis occurs at temperatures above 86°F. Cyclophosphamide monohydrate undergoes both specific acid and specific base catalysis at extreme pHs. Spontaneous hydrolysis in aqueous solutions.
Reactivity Profile Polymerization can occur at temperatures > 120° F. Cyclophosphamide monohydrate reacts with strong oxidizing agents, strong acids and strong bases. Benzyl alcohol increases rate of hydrolysis.
Fire Hazard Cyclophosphamide monohydrate is probably combustible.
 
Cyclophosphamide monohydrate Preparation Products And Raw materials
Raw materials 2,2'-Iminodiethanol

 

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