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CAS NO.599-79-1
| Salicylazosulfapyridine Basic information |
| Product Name: | Salicylazosulfapyridine |
| Synonyms: | salicylazosulfapyridine;SALAZOSULFAPYRIDINE;SULFASALAZINE;SSZ;LABOTEST-BB LT00772281;5-(p-(2-pyridylsulfamoyl)phenylazo)salicylic acid;5-[4-(2-PYRIDYLSULFAMOYL)PHENYLAZO]SALICYLIC ACID;2-hydroxy-5-[[4-[(2-pyridinylamino)sulfonyl]phenyl]azo]benzoic acid |
| CAS: | 599-79-1 |
| MF: | C18H14N4O5S |
| MW: | 398.4 |
| EINECS: | 209-974-3 |
| Product Categories: | APIs;Antibiotics for Research and Experimental Use;Biochemistry;Sulfonamides (Antibiotics for Research and Experimental Use);Intermediates & Fine Chemicals;Pharmaceuticals;Cytokine signaling;Amines;Aromatics;Heterocycles;Sulfur & Selenium Compounds;AZULFIDINE;Other APIs;API |
| Mol File: | 599-79-1.mol |
|
|
|
| Salicylazosulfapyridine Chemical Properties |
| mp | 260-265 °C (dec.)(lit.) |
| storage temp. | Refrigerator |
| solubility | NH4OH 1 M: 50 mg/mL, clear, red |
| Water Solubility | <0.1 g/100 mL at 25 ºC |
| Merck | 8942 |
| CAS DataBase Reference | 599-79-1(CAS DataBase Reference) |
| EPA Substance Registry System | Benzoic acid, 2-hydroxy-5-[[4-[(2-pyridinylamino) sulfonyl]phenyl]azo]-(599-79-1) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 42/43 |
| Safety Statements | 22-29/56-45 |
| WGK Germany | 2 |
| RTECS | VO6250000 |
| F | 8 |
| Hazardous Substances Data | 599-79-1(Hazardous Substances Data) |
| MSDS Information |
| Provider | Language |
|---|---|
| Salicylazosulfapyridine | English |
| SigmaAldrich | English |
| Salicylazosulfapyridine Usage And Synthesis |
| Chemical Properties | Brownish-Yellow Crystals |
| Usage | Anti-inflammatory (gastrointestinal). Has been used in granulomatous colitis. |
| Usage | anticolitis and Crohn's disease |
| Usage | Sulfasalazine is an anti-inflammatory (gastrointestinal). Sulfasalazine has been used in granulomatous colitis. |
| General Description | Odorless yellow or brownish-yellow to orange powder. Tasteless. |
| Air & Water Reactions | Light sensitive and may be sensitive to prolonged exposure to air. Dust can be explosive when suspended in air at specific concentrations. Insoluble in water. |
| Fire Hazard | Flash point data for Salicylazosulfapyridine are not available; however, Salicylazosulfapyridine is probably combustible. |
| Salicylazosulfapyridine Preparation Products And Raw materials |
| Raw materials | Acetic acid glacial-->2-Aminopyridine-->Benzenesulfonyl chloride-->Acetanilide-->Sulfapyridine |
| Salicylazosulfapyridine Basic information |
| Product Name: | Salicylazosulfapyridine |
| Synonyms: | salicylazosulfapyridine;SALAZOSULFAPYRIDINE;SULFASALAZINE;SSZ;LABOTEST-BB LT00772281;5-(p-(2-pyridylsulfamoyl)phenylazo)salicylic acid;5-[4-(2-PYRIDYLSULFAMOYL)PHENYLAZO]SALICYLIC ACID;2-hydroxy-5-[[4-[(2-pyridinylamino)sulfonyl]phenyl]azo]benzoic acid |
| CAS: | 599-79-1 |
| MF: | C18H14N4O5S |
| MW: | 398.4 |
| EINECS: | 209-974-3 |
| Product Categories: | APIs;Antibiotics for Research and Experimental Use;Biochemistry;Sulfonamides (Antibiotics for Research and Experimental Use);Intermediates & Fine Chemicals;Pharmaceuticals;Cytokine signaling;Amines;Aromatics;Heterocycles;Sulfur & Selenium Compounds;AZULFIDINE;Other APIs;API |
| Mol File: | 599-79-1.mol |
|
|
|
| Salicylazosulfapyridine Chemical Properties |
| mp | 260-265 °C (dec.)(lit.) |
| storage temp. | Refrigerator |
| solubility | NH4OH 1 M: 50 mg/mL, clear, red |
| Water Solubility | <0.1 g/100 mL at 25 ºC |
| Merck | 8942 |
| CAS DataBase Reference | 599-79-1(CAS DataBase Reference) |
| EPA Substance Registry System | Benzoic acid, 2-hydroxy-5-[[4-[(2-pyridinylamino) sulfonyl]phenyl]azo]-(599-79-1) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 42/43 |
| Safety Statements | 22-29/56-45 |
| WGK Germany | 2 |
| RTECS | VO6250000 |
| F | 8 |
| Hazardous Substances Data | 599-79-1(Hazardous Substances Data) |
| MSDS Information |
| Provider | Language |
|---|---|
| Salicylazosulfapyridine | English |
| SigmaAldrich | English |
| Salicylazosulfapyridine Usage And Synthesis |
| Chemical Properties | Brownish-Yellow Crystals |
| Usage | Anti-inflammatory (gastrointestinal). Has been used in granulomatous colitis. |
| Usage | anticolitis and Crohn's disease |
| Usage | Sulfasalazine is an anti-inflammatory (gastrointestinal). Sulfasalazine has been used in granulomatous colitis. |
| General Description | Odorless yellow or brownish-yellow to orange powder. Tasteless. |
| Air & Water Reactions | Light sensitive and may be sensitive to prolonged exposure to air. Dust can be explosive when suspended in air at specific concentrations. Insoluble in water. |
| Fire Hazard | Flash point data for Salicylazosulfapyridine are not available; however, Salicylazosulfapyridine is probably combustible. |
| Salicylazosulfapyridine Preparation Products And Raw materials |
| Raw materials | Acetic acid glacial-->2-Aminopyridine-->Benzenesulfonyl chloride-->Acetanilide-->Sulfapyridine |