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CAS NO.58579-51-4
| Anagrelide hydrochloride Basic information |
| Product Name: | Anagrelide hydrochloride |
| Synonyms: | 1-b)quinazolin-2(3h)-one,6,7-dichloro-1,5-dihydro-imidazo(monohydrochlorid;6,7-DICHLORO-1,5-DIHYDROIMIDAZO[2,1-B]QUINAZOLIN-2(3H)-ONE MONOHYDROCHLORIDE;AGRYLIN;ANAGRELIDE HCL;ANAGRELIDE HYDROCHLORIDE;BL-4162A;BMY-26538-01;AnagrelideHclC10H7C12N30.HC1 |
| CAS: | 58579-51-4 |
| MF: | C10H8Cl3N3O |
| MW: | 292.55 |
| EINECS: | |
| Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Bases & Related Reagents;Heterocycles;Nucleotides;Inhibitors |
| Mol File: | 58579-51-4.mol |
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| Anagrelide hydrochloride Chemical Properties |
| mp | >280°C |
| storage temp. | Desiccate at +4°C |
| CAS DataBase Reference | 58579-51-4(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26 |
| Anagrelide hydrochloride Usage And Synthesis |
| Chemical Properties | Off-White Powder |
| Usage | A phosphodiesterase inhibitor with antiplatelet activity. Used as an antithrombocythemic. |
| Usage | Signal Transduction Agents, Potent PDE3 inhibitor |
| Biological Activity | Potent type III phosphodiesterase (PDE3) inhibitor (IC 50 = 36 nM). Inhibits platelet aggregation and produces potent thrombocytopenic effects via inhibition of megakaryocyte maturation. |
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