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CAS NO.58-94-6
| Chlorothiazide Basic information |
| Product Name: | Chlorothiazide |
| Synonyms: | 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-, 1,1-dioxide;2h-1,2,4-benzothiadiazine-7-sulfonamide,6-chloro-,1,1-dioxide;Aldoclor;Alurene;Chloriazid;Chlorosal;Chlorothiazid;Chlorthiazide |
| CAS: | 58-94-6 |
| MF: | C7H6ClN3O4S2 |
| MW: | 295.72 |
| EINECS: | 200-404-9 |
| Product Categories: | Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;DIURIL |
| Mol File: | 58-94-6.mol |
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| Chlorothiazide Chemical Properties |
| Melting point | 342-343°C |
| storage temp. | 2-8°C |
| Water Solubility | <0.1 g/100 mL at 19.5 ºC |
| Merck | 2168 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 58-94-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Chlorothiazide(58-94-6) |
| EPA Substance Registry System | 2H-1,2,4-Benzothiadiazine- 7-sulfonamide, 6-chloro-, 1,1-dioxide(58-94-6) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 42/43-20/21/22 |
| Safety Statements | 36 |
| WGK Germany | 2 |
| RTECS | DK9450000 |
| Hazardous Substances Data | 58-94-6(Hazardous Substances Data) |
| Chlorothiazide Usage And Synthesis |
| Chemical Properties | Off-White Solid |
| Usage | Diuretic; antihypertensive |
| Definition | ChEBI: 4H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position is substituted by chlorine and that at position 7 is substituted by a sulfonamide group. A diuretic, it is used for treatment of oedema and hypertension. |
| General Description | Crystals; white powder. |
| Air & Water Reactions | Insoluble in water. |
| Reactivity Profile | Alkaline aqueous solutions will decompose on standing or heating . |
| Fire Hazard | Flash point data for Chlorothiazide are not available; however, Chlorothiazide is probably combustible. |
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