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CAS NO.55-03-8
Levothyroxine sodium Basic information |
Product Name: | Levothyroxine sodium |
Synonyms: | SODIUM (S)-2-AMINO-3-[4-(4-HYDROXY-3,5-DIIODOPHENOXY)-3,5-DIIODOPHENYL]PROPIONATE PENTAHYDRATE;(S)-2-AMINO-3-[4-(4-HYDROXY-3,5-DIIODOPHENOXY)-3,5-DIIODOPHENYL]PROPIONIC ACID SODIUM SALT PENTAHYDRATE;3-[4-(4-HYDROXY-3,5-DIIODOPHENOXY)-3,5-DIIODOPHENYL]-L-ALANINE SODIUM SALT PENTAHYDRATE;3-[4-(4-HYDROXY-3,5-DIIODOPHENOXY)-3,5-DIIODOPHENYL]-L-ALANINE PENTAHYDRATE;L-THYROXINE SODIUM SALT PENTAHYDRATE;L-THYROXINE SODIUM PENTAHYDRATE;3-Amino-4-(4-(4-OH-3,5-diiodophenoxy)-3,5-diiodophenyl))but.ac.Na salt;L-ThyroxineSodiumSaltB.P. |
CAS: | 55-03-8 |
MF: | C15H20I4NNaO9 |
MW: | 888.93 |
EINECS: | 200-221-4 |
Product Categories: | Medicine intermediate;Amino Acids;Biochemistry;Biological-modified Amino Acids;Amino Acids & Derivatives;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone |
Mol File: | 55-03-8.mol |
Levothyroxine sodium Chemical Properties |
mp | 207-210 (dec.)(lit.) |
storage temp. | 2-8°C |
solubility | cell culture medium: 0.1 mg/mL |
form | powder |
EPA Substance Registry System | L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)- 3,5-diiodo-, monosodium salt(55-03-8) |
Safety Information |
Safety Statements | 22-24/25 |
RIDADR | 2811 |
WGK Germany | 3 |
RTECS | YP2833760 |
F | 3-8-10 |
HazardClass | 6.1(a) |
PackingGroup | II |
MSDS Information |
Provider | Language |
---|---|
ACROS | English |
SigmaAldrich | English |
Levothyroxine sodium Usage And Synthesis |
Chemical Properties | White Solid |
Usage | One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia. |
Levothyroxine sodium Preparation Products And Raw materials |
Raw materials | Acetic acid glacial-->L-Thyroxine-->Sodium levothyroxine |