Name: 538-75-0 C13H22N2 Dicyclohexylcarbodiimide
SKU: 538-75-0
Availability: InStock

Keywords

538-75-0 C13H22N2 Dicyclohexylcarbodiimide
538-75-0
C13H22N2

Quick Details

ProName: 538-75-0 C13H22N2 Dicyclohexylcarbod...
CasNo: 538-75-0
Molecular Formula: C13H22N2
Appearance: white powder
Application: N,N'-Dicyclohexylcarbodiimide is a car...
DeliveryTime: 5-7 days after payment
PackAge: Woven bag
Port: Tianjin Shanghai
ProductionCapacity: 2 Kilogram/Day
Purity: 99%
Storage: Normal temperature
Transportation: Ocean shipping Express delivery
LimitNum: 10 Gram

Superiority

Dicyclohexylcarbodiimide Basic information

Product Name:	Dicyclohexylcarbodiimide
Synonyms:	Carbodicyclohexylimide;Carbodiimide, dicyclohexyl-;Dicyclimide;dicyclohexyl-carbodiimid;n,n’-dicyclohexylcarbodiimide,1msol.inn-methylpyrrolidone,peptidesynthesisgrade;n,n’-methanetetraylbis-cyclohexaamin;n,n’-methanetetraylbis-cyclohexanamin;N,N’-methanetetraylbis-Cyclohexanamine
CAS:	538-75-0
MF:	C13H22N2
MW:	206.33
EINECS:	208-704-1
Product Categories:	Pharmaceutical Intermediates;Amino Acid Derivatives;Starting Raw Materials & Intermediates;Miscellaneous;Organics;Coupling Reagent;Peptide Coupling Reagents;Condensing Agents (DNA / RNA Synthesis);Biochemistry;Condensation & Active Esterification;Coupling Reactions (Peptide Synthesis);Nucleosides, Nucleotides & Related Reagents;Peptide Synthesis;Protecting Agents, Phosphorylating Agents & Condensing Agents;Reagents for Oligosaccharide Synthesis;Synthetic Organic Chemistry;Peptide;Protected Amino Acids;Synthetic Reagents;CarbodiimidesSynthetic Reagents;Carbodiimides;Coupling;Peptide Synthesis;peptides;Zero-Length Crosslinker
Mol File:	538-75-0.mol

Dicyclohexylcarbodiimide Chemical Properties

mp	34-35 °C(lit.)
bp	122-124 °C6 mm Hg(lit.)
density	1.247 g/mL at 25 °C
refractive index	n20/D 1.48
Fp	190 °F
storage temp.	Store at RT.
solubility	methylene chloride: 0.1 g/mL, clear, colorless
Water Solubility	Reaction
Sensitive	Moisture Sensitive
Merck	14,3096
BRN	610662
Stability:	Stable, but moisture sensitive. Combustible. Incompatible with strong oxidizing agents. Avoid exposure to air or moisture.
CAS DataBase Reference	538-75-0(CAS DataBase Reference)
NIST Chemistry Reference	Methanediimine, n,n'-dicyclohexyl-(538-75-0)
EPA Substance Registry System	Cyclohexanamine, N,N'-methanetetraylbis- (538-75-0)

Safety Information

Hazard Codes	T,Xn,T+
Risk Statements	23/24/25-34-40-43-41-36/38-21-24-22-62-37/38-10-61-26-38-20/22
Safety Statements	26-36/37/39-45-41-24-37/39-24/25-36-16-53-28
RIDADR	UN 2922 8/PG 2
WGK Germany	3
RTECS	FF2160000
F	3-8-10-21
HazardClass	6.1
PackingGroup	II
HS Code	29252000

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

Dicyclohexylcarbodiimide Usage And Synthesis

Chemical Properties	Colorless solid
Usage	This product is mainly used in amikacin, glutathione dehydrants, as well as in synthesis of acid anhydride, aldehyde, ketone, isocyanate; when it is used as dehydrating condensing agent, it reacts to dicyclohexylurea through short-time reaction under normal temperature. This product can also be used in synthesis of peptide and nucleic acid. It is easy to use this product to react with compound of free carboxy and amino-group into peptide. This product is widely used in medical, health, make-up and biological products, and other synthetic fields.
Usage	N,N'-Dicyclohexylcarbodiimide is a carbodiimide used to couple amino acids during peptide synthesis. N,N'-Dicyclohexylcarbodiimide is used as a dehydrating agent for the preparation of amides, ketones , nitriles as well as in the inversion and esterification of secondary alcohols.
Usage	dicyclohexylcarbodiimide is used as a dehydrating agent at room temperature after a short reaction time, after the reaction product is dicyclohexylurea. the product is very small solubility in an organic solvent, so that easy separation of the reaction product.
General Description	White crystalline solid with a heavy sweet odor.
Air & Water Reactions	Sensitive to moisture.
Reactivity Profile	Dicyclohexylcarbodiimide is an imide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx). Dicyclohexylcarbodiimide is incompatible with acids and oxidizing agents. Dicyclohexylcarbodiimide reacts with water.
Fire Hazard	Dicyclohexylcarbodiimide is probably combustible.

Dicyclohexylcarbodiimide Preparation Products And Raw materials

Preparation Products

(S)-3-Aminoquinuclidine dihydrochloride-->Enalapril-->GLY-7-AMINO-4-METHYLCOUMARIN-->2-CYANOPYRIDINE-4-CARBOXALDEHYDE-->H-BETA-ALA-OTBU HCL-->NAPHTHOL AS-BI PHOSPHATE-->Captopril-->2,6-DICHLOROPHENETHYLISOCYANIDE-->1-(2-ISOCYANO-ETHYL)-4-METHYL-PIPERAZINE-->TERT-BUTYL METHYL MALONATE-->Isobutyric anhydride-->Lisinopril-->2-MORPHOLINOISONICOTINALDEHYDE-->1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino] acetyl] amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-en-3-yl]methyl]pyridinum hydroxide inner salt-->7-DIETHYLAMINO-3-THENOYLCOUMARIN-->Cefprozil hydrate-->4-ISOCYANOBENZOPHENONE-->TERT-BUTYL 3-HYDROXYPROPIONATE-->Docetaxel-->Cyclic AMP-->ANGIOTENSIN II, HUMAN-->3-CARBETHOXY-4-HYDROXYCOUMARIN-->7-(((2-Amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((5-(carboxymethyl)-4-methyl-2-thiazolyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid-->Beraprost-->Octreotide acetate-->Trandolapril-->Tetrabenzyl pyrophosphate-->Paroxetine-->Benexate Hydrochloride-->IBUTILIDE-->Latanoprost

Raw materials

Azabenzene-->Urea-->Carbon disulphide-->Cyclohexylamine-->DCHA-->N,N'-DICYCLOHEXYLUREA-->1,3-Dicyclohexylthiourea

Details

Dicyclohexylcarbodiimide Basic information

Product Name:	Dicyclohexylcarbodiimide
Synonyms:	Carbodicyclohexylimide;Carbodiimide, dicyclohexyl-;Dicyclimide;dicyclohexyl-carbodiimid;n,n’-dicyclohexylcarbodiimide,1msol.inn-methylpyrrolidone,peptidesynthesisgrade;n,n’-methanetetraylbis-cyclohexaamin;n,n’-methanetetraylbis-cyclohexanamin;N,N’-methanetetraylbis-Cyclohexanamine
CAS:	538-75-0
MF:	C13H22N2
MW:	206.33
EINECS:	208-704-1
Product Categories:	Pharmaceutical Intermediates;Amino Acid Derivatives;Starting Raw Materials & Intermediates;Miscellaneous;Organics;Coupling Reagent;Peptide Coupling Reagents;Condensing Agents (DNA / RNA Synthesis);Biochemistry;Condensation & Active Esterification;Coupling Reactions (Peptide Synthesis);Nucleosides, Nucleotides & Related Reagents;Peptide Synthesis;Protecting Agents, Phosphorylating Agents & Condensing Agents;Reagents for Oligosaccharide Synthesis;Synthetic Organic Chemistry;Peptide;Protected Amino Acids;Synthetic Reagents;CarbodiimidesSynthetic Reagents;Carbodiimides;Coupling;Peptide Synthesis;peptides;Zero-Length Crosslinker
Mol File:	538-75-0.mol

Dicyclohexylcarbodiimide Chemical Properties

mp	34-35 °C(lit.)
bp	122-124 °C6 mm Hg(lit.)
density	1.247 g/mL at 25 °C
refractive index	n20/D 1.48
Fp	190 °F
storage temp.	Store at RT.
solubility	methylene chloride: 0.1 g/mL, clear, colorless
Water Solubility	Reaction
Sensitive	Moisture Sensitive
Merck	14,3096
BRN	610662
Stability:	Stable, but moisture sensitive. Combustible. Incompatible with strong oxidizing agents. Avoid exposure to air or moisture.
CAS DataBase Reference	538-75-0(CAS DataBase Reference)
NIST Chemistry Reference	Methanediimine, n,n'-dicyclohexyl-(538-75-0)
EPA Substance Registry System	Cyclohexanamine, N,N'-methanetetraylbis- (538-75-0)

Safety Information

Hazard Codes	T,Xn,T+
Risk Statements	23/24/25-34-40-43-41-36/38-21-24-22-62-37/38-10-61-26-38-20/22
Safety Statements	26-36/37/39-45-41-24-37/39-24/25-36-16-53-28
RIDADR	UN 2922 8/PG 2
WGK Germany	3
RTECS	FF2160000
F	3-8-10-21
HazardClass	6.1
PackingGroup	II
HS Code	29252000

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

Dicyclohexylcarbodiimide Usage And Synthesis

Chemical Properties	Colorless solid
Usage	This product is mainly used in amikacin, glutathione dehydrants, as well as in synthesis of acid anhydride, aldehyde, ketone, isocyanate; when it is used as dehydrating condensing agent, it reacts to dicyclohexylurea through short-time reaction under normal temperature. This product can also be used in synthesis of peptide and nucleic acid. It is easy to use this product to react with compound of free carboxy and amino-group into peptide. This product is widely used in medical, health, make-up and biological products, and other synthetic fields.
Usage	N,N'-Dicyclohexylcarbodiimide is a carbodiimide used to couple amino acids during peptide synthesis. N,N'-Dicyclohexylcarbodiimide is used as a dehydrating agent for the preparation of amides, ketones , nitriles as well as in the inversion and esterification of secondary alcohols.
Usage	dicyclohexylcarbodiimide is used as a dehydrating agent at room temperature after a short reaction time, after the reaction product is dicyclohexylurea. the product is very small solubility in an organic solvent, so that easy separation of the reaction product.
General Description	White crystalline solid with a heavy sweet odor.
Air & Water Reactions	Sensitive to moisture.
Reactivity Profile	Dicyclohexylcarbodiimide is an imide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx). Dicyclohexylcarbodiimide is incompatible with acids and oxidizing agents. Dicyclohexylcarbodiimide reacts with water.
Fire Hazard	Dicyclohexylcarbodiimide is probably combustible.

Dicyclohexylcarbodiimide Preparation Products And Raw materials

Preparation Products

(S)-3-Aminoquinuclidine dihydrochloride-->Enalapril-->GLY-7-AMINO-4-METHYLCOUMARIN-->2-CYANOPYRIDINE-4-CARBOXALDEHYDE-->H-BETA-ALA-OTBU HCL-->NAPHTHOL AS-BI PHOSPHATE-->Captopril-->2,6-DICHLOROPHENETHYLISOCYANIDE-->1-(2-ISOCYANO-ETHYL)-4-METHYL-PIPERAZINE-->TERT-BUTYL METHYL MALONATE-->Isobutyric anhydride-->Lisinopril-->2-MORPHOLINOISONICOTINALDEHYDE-->1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino] acetyl] amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-en-3-yl]methyl]pyridinum hydroxide inner salt-->7-DIETHYLAMINO-3-THENOYLCOUMARIN-->Cefprozil hydrate-->4-ISOCYANOBENZOPHENONE-->TERT-BUTYL 3-HYDROXYPROPIONATE-->Docetaxel-->Cyclic AMP-->ANGIOTENSIN II, HUMAN-->3-CARBETHOXY-4-HYDROXYCOUMARIN-->7-(((2-Amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((5-(carboxymethyl)-4-methyl-2-thiazolyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid-->Beraprost-->Octreotide acetate-->Trandolapril-->Tetrabenzyl pyrophosphate-->Paroxetine-->Benexate Hydrochloride-->IBUTILIDE-->Latanoprost

Raw materials

Azabenzene-->Urea-->Carbon disulphide-->Cyclohexylamine-->DCHA-->N,N'-DICYCLOHEXYLUREA-->1,3-Dicyclohexylthiourea

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538-75-0 C13H22N2 Dicyclohexylcarbodiimide

Product Details

Keywords

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