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CAS NO.530-43-8
| Chloramphenicol palmitate Basic information |
| Product Name: | Chloramphenicol palmitate |
| Synonyms: | CHLORAMPHENICOL ALPHA-PALMITATE;CHLORAMPHENICOL PALMITATE;alpha-esterwithd-threo-(-)-2,2-dichloro-n-(beta-hydroxy-alpha-palmiticaci;cap-p;cap-palmitate;chloramphenicolmonopalmitate;chloramphenicolpalmitate(ester);chloromycetinpalmitate |
| CAS: | 530-43-8 |
| MF: | C27H42Cl2N2O6 |
| MW: | 561.54 |
| EINECS: | 208-477-9 |
| Product Categories: | BacteriostaticAlphabetic;CHAntibiotics;Standards for SupelMIPTM SPE;Antibiotics;C;Chemical Structure;Chromatography;OthersAnalytical Standards;Principle;CHLOROPAL |
| Mol File: | 530-43-8.mol |
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| Chloramphenicol palmitate Chemical Properties |
| Melting point | 90 C |
| storage temp. | Store at RT. |
| Merck | 13,2087 |
| CAS DataBase Reference | 530-43-8(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 40-36/37/38-20/21/22 |
| Safety Statements | 36/37-36-26 |
| RTECS | RT4735000 |
| HS Code | 29414000 |
| Chloramphenicol palmitate Usage And Synthesis |
| Chemical Properties | white crystals |
| Usage | antibacterial, antirickettsial |
| Usage | Chloramphenicol palmitate is prepared by acylation of chloramphenicol with palmitic acid. Although chloramphenicol palmitate is a more hydrophobic drug which should enhance bioavailability, the primary advantage of the ester is to mask the taste of chloramphenicol in oral formulations. Chloramphenicol palmitate is significantly less active than chloramphenicol but acts as a prodrug, being readily hydrolysed by acid and esterase in the gut to release chloramphenicol. |
| Chloramphenicol palmitate Preparation Products And Raw materials |
| Raw materials | Thionyl chloride-->Benzene-->2-Picoline-->Palmitic acid-->Chloramphenicol-->Palmitoyl chloride |
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