HENAN SUNLAKE ENTERPRISE CORPORATION
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Country: 
China (Mainland)
Business Type:Trading Company
Tel: +86-371- 86259723
Tel: 17734809689
Tel: 17734809689
Tel: 86-371-86259723
Tel: 17734809689
Tel: 17734809689
Mobile: 17734809689
Tel: +86-371- 86259723
Fax: +86-371- 86259723
Province/state: HENAN
City: ZHENGZHOU
Street: Mingmen International Center, NO.222 Dongming Road,Zhengzhou,Henan,China
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1.Certificate Of Analysis (COA)
2.Material Safety Data Sheet (MSDS)
3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)
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3. Packing as your request, with photo before shipment
4. Mixed containers with different mixed items in one container
About Company
| Product Name: | Diosmin |
| Synonyms: | DIOSMETIN-7-O-RUTINOSIDE;DIOSMETIN-7-RUTINOSIDE;DIOSMIN;BAROSMIN;3',5,7-TRIHYDROXY-4'-METHOXYFLAVONE 7-RUTINOSIDE;3,5,7-TRIHYDROXY-4-METHOXYFLAVONE 7-RUTINOSIDE;Diosmine EP4;DIOSMINE |
| CAS: | 520-27-4 |
| MF: | C28H32O15 |
| MW: | 608.54 |
| EINECS: | 208-289-7 |
| Product Categories: | Tetra-substituted Flavones;plant extract;ACTIVE PHARMACEUTICAL INGREDIENTS;Aromatics;Intermediates & Fine Chemicals;Oligosaccharides;Pharmaceuticals;Plant extracts;Herb extract;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;DIOSMIL;Inhibitors |
| Mol File: | 520-27-4.mol |
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| Diosmin Chemical Properties |
| mp | 277-278°C |
| storage temp. | 2-8°C |
| Merck | 13,3327 |
| CAS DataBase Reference | 520-27-4(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-36/37 |
| WGK Germany | 3 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| Diosmin Usage And Synthesis |
| Pharmacological Effects |
Diosmin is also called Alvenor. It is a kind of drug for the treatment of hemorrhoid symptoms related to acute episodes, can also be used in the treatment of symptoms associated with venous lymphatic insufficiency (leg heavy, pain, morning acid swells discomfort). The effects of diosmin are as below: 1, Has specific affinity to the venous system, enhance the tension system without affecting the artery of vein; 2, To the microcirculation system, decrease the blood viscosity, improve the velocity of reducing silt up; 3, Contract the lymphatic system, which can enhance lymphatic and lymph drainage speed, speed up the return relieve edema. 4, Commercially available diosmin uses micronization technology, increase the contact area after using medicine, absorb more and higher bioavailability. Suitable for all kinds of hemorrhoids and acute hemorrhoids, also can be used for the treatment of chronic venous insufficiency, such as varicose veins, leg ulcers, etc. This information is edited by ChemicalBook Xiao Nan. |
| Side Effects |
1, May appear nausea, vomiting, abdominal pain, dyspepsia, diarrhea, insomnia, dizziness, headache, drowsiness, anxiety and other adverse reactions. 2, There may be a few of minor gastrointestinal reactions and adverse reactions such as plant nerve function disorder, but generally mild and don't have to stop the drug. 3, Pregnant women and nursing mothers with hemorrhoids are safe to use this product. |
| Taboos | People who allergy to any ingredients in this product are prohibited. |
| Attentions |
Hemorrhoid acute episodes: treatment with this drug can't replace any other special treatments needed for handling anus diseases. This treatment must be short. If symptoms cannot eliminate quickly, anorectal epidemiology check and review should be needed. This product contains flavonoids which is the effective composition of glycosides in plants. Effective flavonoid content for each piece of diosmin is 450 mg, 50 mg of hesperidin, the total flavonoid glycosides composition (also called Daflon) is 500 mg. General flavonoids have certain biological activity, but low toxicity and rare allergic reactions, if any allergies, stop the drug. |
| Application |
Used in food, medicine, health products, etc Action mechanism: 1.Enhance the vein tension, even not exceptional under high temperature condition. It has a stronger effect causing the constriction of vein than other drugs such as rutin, still can enhance the tension of the vein when the body was acidosis. Diosmin has specific affinity for vein without affecting the arterial system. 2. Improve microcirculation. Diosmin can obviously reduce the white blood cells and vascular endothelial cell adhesion, migration, disintegrating the release of inflammatory substances, such as histamine, slow excitation peptide, complement, leukotriene, prostaglandins, and too many free radicals, reducing the permeability of capillaries and enhance its tension. Diosmin can lower blood viscosity, enhance the function of red blood cell velocity, thus reduce the microcirculation clogged. 3. Promote lymphatic circumfluence. Diosmin can increase the speed of lymphatic drainage. |
| Pregnant Women and Nursing Mothers Drug Use |
Pregnancy women use: animal experiments did not show any teratogenic effects. So far, still no harmful reports to human. Delivery: there is no detailed research data. Nursing mothers use: although there is no information on drug secreted with breast milk, but treatment is not recommended during breastfeeding. |
| Chemical Properties | Brown powder |
| Usage | vascular protectant |
| Usage | Naturally occurring flavonic glycoside; rhamnoglycoside of Diosmetin. Capillary protectant |
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Diosmin Preparation Products And Raw materials |