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CAS NO.51-48-9
1(10-100)Metric Ton1(10-100)Metric Ton
| L-Thyroxine Basic information |
| Product Name: | L-Thyroxine |
| Synonyms: | 3,5,3’,5’-tetraiodothyronine;beta-[(3,5-diiodo-4-hydroxyphenoxy)-3,5-diiodophenyl]alanine;l-3,5,3’,5’-tetraiodothyronine;l-t4;o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-l-tyrosin;o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine;t4(hormone);tetraiodothyronine |
| CAS: | 51-48-9 |
| MF: | C15H11I4NO4 |
| MW: | 776.87 |
| EINECS: | 200-101-1 |
| Product Categories: | Amino Acids;Organics;Heterocyclic Compounds;Amino Acids & Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labeled Compounds;Aromatics;Isotope Labelled Compounds;SYNTHROID;Isolabel;Other APIs;Inhibitors |
| Mol File: | 51-48-9.mol |
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| L-Thyroxine Chemical Properties |
| mp | 235 °C |
| alpha | -5 º (1N NaOH:EtOH 1:2) |
| storage temp. | 2-8°C |
| Water Solubility | insoluble |
| Merck | 9491 |
| CAS DataBase Reference | 51-48-9(CAS DataBase Reference) |
| EPA Substance Registry System | L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)- 3,5-diiodo-(51-48-9) |
| Safety Information |
| Hazard Codes | Xn,T,F |
| Risk Statements | 40-39/23/24/25-23/24/25-11 |
| Safety Statements | 22-24/25-36-45-36/37-16 |
| WGK Germany | 3 |
| RTECS | YP2833500 |
| F | 8-10 |
| HazardClass | IRRITANT |
| Hazardous Substances Data | 51-48-9(Hazardous Substances Data) |
| MSDS Information |
| Provider | Language |
|---|---|
| 3,3',5,5'-Tetraiodo-L-thyronine | English |
| SigmaAldrich | English |
| ACROS | English |
| L-Thyroxine Usage And Synthesis |
| Chemical Properties | Crystalline Solid |
| Usage | antihypercholesterimic, thyromimetic |
| Usage | One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroi d hormone, but has been used to treat hyperlipidemia. |
| L-Thyroxine Preparation Products And Raw materials |
| Raw materials | 3,5-Diiodo-L-tyrosine dihydrate |
| Preparation Products | Levothyroxine sodium |
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