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CAS NO.51-20-7
| 5-Bromouracil Basic information |
| Product Name: | 5-Bromouracil |
| Synonyms: | BROMOURACIL;BROMOURACIL, 5-;BUTTPARK 48\06-06;5-BROMO-2,4-DIHYDROXYPYRIMIDINE;5-BROMO-2,3-DIHYDROXYPYRIMIDINE;5-BROMO-2,4-(1H,3H)-PYRIMIDINEDIONE;5-BROMO-1H-PYRIMIDINE-2,4-DIONE;5-BROMOPYRIMIDINE-2,4-DIOL |
| CAS: | 51-20-7 |
| MF: | C4H3BrN2O2 |
| MW: | 190.98 |
| EINECS: | 200-084-0 |
| Product Categories: | Pyrimidine series;Detergents;Biochemistry;Nucleobases and their analogs;Nucleosides, Nucleotides & Related Reagents;Nucleic acids;Bases & Related Reagents;Mutagenesis Research Chemicals;Nucleotides |
| Mol File: | 51-20-7.mol |
|
|
|
| 5-Bromouracil Chemical Properties |
| mp | >300 °C(lit.) |
| storage temp. | -20°C Freezer |
| Water Solubility | SOLUBLE IN COLD WATER |
| Merck | 14,1440 |
| BRN | 127176 |
| CAS DataBase Reference | 51-20-7(CAS DataBase Reference) |
| NIST Chemistry Reference | 5-Bromouracil(51-20-7) |
| EPA Substance Registry System | 2,4(1H,3H)-Pyrimidinedione, 5-bromo-(51-20-7) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 22-46 |
| Safety Statements | 36/37-53-45 |
| WGK Germany | 3 |
| RTECS | YQ9060000 |
| HS Code | 29335995 |
| Hazardous Substances Data | 51-20-7(Hazardous Substances Data) |
| MSDS Information |
| Provider | Language |
|---|---|
| 5-Bromo-2,4(1H,3H)-pyrimidinedione | English |
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| 5-Bromouracil Usage And Synthesis |
| Chemical Properties | Prisms |
| Usage | A major chemical mutagen. Incorporates into DNA, altering base-pair sequencing by replacing thymine |
| General Description | White powder. |
| Air & Water Reactions | Insoluble in water. |
| Reactivity Profile | A halogenated amide. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx). |
| Health Hazard | ACUTE/CHRONIC HAZARDS: When heated to decomposition 5-Bromouracil emits very toxic fumes of bromide ion and NOx. |
| Fire Hazard | Flash point data for 5-Bromouracil are not available, but 5-Bromouracil is probably combustible. |
| 5-Bromouracil Preparation Products And Raw materials |
| Preparation Products | 5-BROMO-2-CHLORO-4-(DIMETHYLAMINO)PYRIMIDINE-->5-BROMO-2,4-DIMETHOXYPYRIMIDINE |
| Raw materials | 1,4-Dioxane-->L-Alanine |
| 5-Bromouracil Basic information |
| Product Name: | 5-Bromouracil |
| Synonyms: | BROMOURACIL;BROMOURACIL, 5-;BUTTPARK 48\06-06;5-BROMO-2,4-DIHYDROXYPYRIMIDINE;5-BROMO-2,3-DIHYDROXYPYRIMIDINE;5-BROMO-2,4-(1H,3H)-PYRIMIDINEDIONE;5-BROMO-1H-PYRIMIDINE-2,4-DIONE;5-BROMOPYRIMIDINE-2,4-DIOL |
| CAS: | 51-20-7 |
| MF: | C4H3BrN2O2 |
| MW: | 190.98 |
| EINECS: | 200-084-0 |
| Product Categories: | Pyrimidine series;Detergents;Biochemistry;Nucleobases and their analogs;Nucleosides, Nucleotides & Related Reagents;Nucleic acids;Bases & Related Reagents;Mutagenesis Research Chemicals;Nucleotides |
| Mol File: | 51-20-7.mol |
|
|
|
| 5-Bromouracil Chemical Properties |
| mp | >300 °C(lit.) |
| storage temp. | -20°C Freezer |
| Water Solubility | SOLUBLE IN COLD WATER |
| Merck | 14,1440 |
| BRN | 127176 |
| CAS DataBase Reference | 51-20-7(CAS DataBase Reference) |
| NIST Chemistry Reference | 5-Bromouracil(51-20-7) |
| EPA Substance Registry System | 2,4(1H,3H)-Pyrimidinedione, 5-bromo-(51-20-7) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 22-46 |
| Safety Statements | 36/37-53-45 |
| WGK Germany | 3 |
| RTECS | YQ9060000 |
| HS Code | 29335995 |
| Hazardous Substances Data | 51-20-7(Hazardous Substances Data) |
| MSDS Information |
| Provider | Language |
|---|---|
| 5-Bromo-2,4(1H,3H)-pyrimidinedione | English |
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| 5-Bromouracil Usage And Synthesis |
| Chemical Properties | Prisms |
| Usage | A major chemical mutagen. Incorporates into DNA, altering base-pair sequencing by replacing thymine |
| General Description | White powder. |
| Air & Water Reactions | Insoluble in water. |
| Reactivity Profile | A halogenated amide. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx). |
| Health Hazard | ACUTE/CHRONIC HAZARDS: When heated to decomposition 5-Bromouracil emits very toxic fumes of bromide ion and NOx. |
| Fire Hazard | Flash point data for 5-Bromouracil are not available, but 5-Bromouracil is probably combustible. |
| 5-Bromouracil Preparation Products And Raw materials |
| Preparation Products | 5-BROMO-2-CHLORO-4-(DIMETHYLAMINO)PYRIMIDINE-->5-BROMO-2,4-DIMETHOXYPYRIMIDINE |
| Raw materials | 1,4-Dioxane-->L-Alanine |