HENAN SUNLAKE ENTERPRISE CORPORATION
Free supplier Enterprise Certification
- Free
supplier - 9th
years
Free supplier Enterprise Certification
Product Certification&
Enterprise Certification
Country: 
China (Mainland)
Business Type:Trading Company
Tel: +86-371- 86259723
Tel: 17734809689
Tel: 17734809689
Tel: 86-371-86259723
Tel: 17734809689
Tel: 17734809689
Mobile: 17734809689
Tel: +86-371- 86259723
Fax: +86-371- 86259723
Province/state: HENAN
City: ZHENGZHOU
Street: Mingmen International Center, NO.222 Dongming Road,Zhengzhou,Henan,China
MaxCard:
Contact Suppliers
CAS NO.50-03-3
| Hydrocortisone acetate Basic information |
| Product Name: | Hydrocortisone acetate |
| Synonyms: | (11beta)-21-(Acetoxy)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione;11,17-Dihydroxy-3,20-dioxopregn-4-en-21-yl acetate;11-beta,17-alpha-dihydroxy-21-acetoxypregesterone;11beta17alpha-Dihydroxy-21-acetoxypregesterone;17-alpha-hydrocorticosterone21-acetate;17alpha-Hydrocorticosterone-21-acetate;17-dihydroxy-20-dion(11-beta)-pregn-4-ene-21-(acetoxy)-11;17-dihydroxy-20-dion(11beta)-pregn-4-ene-21-(acetyloxy)-11 |
| CAS: | 50-03-3 |
| MF: | C23H32O6 |
| MW: | 404.5 |
| EINECS: | 200-004-4 |
| Product Categories: | Biochemistry;Hydroxyketosteroids;Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Veterinaries;Steroid and Hormone;Hormone Drugs;Adrenal cortical hormone drugs;API |
| Mol File: | 50-03-3.mol |
|
|
|
| Hydrocortisone acetate Chemical Properties |
| Melting point | 223 °C (dec.)(lit.) |
| Fp | 223°C |
| storage temp. | 0-6°C |
| Decomposition | 223 ºC |
| Merck | 14,4787 |
| BRN | 2066841 |
| Stability: | Stable, but may be light or moisture sensitive. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 50-03-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Hydrocortisone acetate(50-03-3) |
| Safety Information |
| Hazard Codes | Xn,T |
| Risk Statements | 63-10-45 |
| Safety Statements | 36/37-45-53 |
| WGK Germany | 3 |
| RTECS | GM8960000 |
| Hydrocortisone acetate Usage And Synthesis |
| Adrenocorticotropic hormone drugs |
Hydrocortisone acetate is an adrenal hormone drugs, white crystalline powder, odorless, bitter taste. The melting point is 216 ~ 222 ℃, right optical. Slightly soluble in ethanol, ether, chloroform, acetone, insoluble in water. It was synthesized by In 17α- hydroxy progesterone. Hydrocortisone acetate has important physiological activities such as anti-inflammatory, anti-viral, anti-allergic, anti-shock, reducing inflammatory exudation effect, commonly used in clinical adrenal insufficiency and autoimmune diseases. Preparations are injection, tablets, ointments and eye drops. Adding a small amount of hydrocortisone acetate in some cosmetics cortisol can increase the efficacy of anti-allergy and improve the degree of whitening of the skin, but long-term using of such substances can cause the skin produce hormone-dependent disease. Our cosmetics cosmetics specifications prescribedthathormone substances can not be added. |
| Indications |
For allergic, non-infectious skin diseases and a number of proliferative skin disorders. Such as dermatitis, eczema, neurodermatitis, seborrheic dermatitis and itching psychosis. Figure 1 the chemical structure formula of tetra-fluoroethane. |
| Contraindications |
1. This medicine and matrix components allergy and allergic to other glucocorticoids are prohibited. 2. The primary bacterial, fungal and viral infectious skin diseases such as disabledare prohibited. The above information is edited by the chemicalbook of KuiMing. |
| Adverse Reactions | Long-term using can cause local skin atrophy, telangiectasia, pigmentation, folliculitis, perioral dermatitis and secondary infection. |
| Precautions |
1. Not long-term, large-scale use. 2. The coated parts such as a burning sensation, itching, swelling, etc., should stop the medication. |
| Chemical Property | White or almost white crystalline powder, odorless. Mp218-221.5 ℃; 25D + 166 ° (dioxane) Specific rotation [α]; ethanol maximum absorption at 240nm wavelength. Insoluble in water, slightly soluble in ethanol (1: 230) and chloroform (1: 150), insoluble in ether. |
| Uses | Corticosteroid drugs, have anti-inflammatory, anti-allergic, anti-toxins, anti-shock effect. |
| Production methods | Hydrocortisone and acetic anhydride in pyridine esterification. |
| Chemical Properties | white powder |
| Usage | Glucocorticoid |
| Hydrocortisone acetate Preparation Products And Raw materials |
| Raw materials | Azabenzene-->Hydrocortisone-->Saponin |
We have clients throughout the world：
Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet your desire.
Our Laboratoy
We have our own independent lab test center：
This makes sure that our technology support is reliable and authoritative.All of self-owned fine chemicals are manufactured strictly in accordance with international standard.,and also has scientific cooperation with local colleges and institutes.
Our factory
High quality with competitive price：
We are manufacturer and can provide high quality products with factory price
Package & Shipment
Fast and safe delivery：
Parcels can be sent out within 24 hours after payment. Tracking number is available
Secure and discreet shipment. You have various choices of transportation methods
