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CAS NO.458-37-7
1(10-100)Kilogram1(101-500)Kilogram2(500-1000)Kilogram
1. Certificate Of Analysis (COA)
2. Material Safety Data Sheet (MSDS)
3. Route of synthesis (ROS)
4. Method of Aanlysis (MOA)
5. Nuclear Magnetic Resonance (NMR)
6. Packing pictures and loading video before loading
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| Curcumin Basic information |
| Product Name: | Curcumin |
| Synonyms: | Curcumin (mixture of curcumin;TURMERIC EXTRACT;1,6-Heptadiene-3,5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)-,(E,E)-;5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)-,(e,e)-6-heptadiene-3;5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)-6-heptadiene-3;6-Heptadiene-3,5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)-,(E,E)-1;curcuma;haidr |
| CAS: | 458-37-7 |
| MF: | C21H20O6 |
| MW: | 368.38 |
| EINECS: | 207-280-5 |
| Product Categories: | Miscellaneous Natural Products;Analytical Chemistry;Antioxidant;Biochemistry;Indicator (pH);pH Indicators;Colorants;Natural Plant Extract;Aromatics;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Diferuloylmethane, Natural Yellow 3, C.I. 75300;pigment |
| Mol File: | 458-37-7.mol |
|
|
|
| Curcumin Chemical Properties |
| mp | 183 °C |
| density | 0.93 |
| vapor density | 13 (vs air) |
| refractive index | 1.4155-1.4175 |
| storage temp. | −20°C |
| solubility | ethanol: 10 mg/mL |
| form | powder |
| Colour Index | 75300 |
| color | orange |
| Water Solubility | Slightly soluble (hot) |
| Merck | 14,2673 |
| BRN | 2306965 |
| Stability: | Stable, but may be light sensitive. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 458-37-7(CAS DataBase Reference) |
| EPA Substance Registry System | 1,6-Heptadiene-3, 5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (1E,6E)-(458-37-7) |
| Safety Information |
| Hazard Codes | Xi,F |
| Risk Statements | 36/37/38-11 |
| Safety Statements | 26-36-16-7 |
| WGK Germany | 2 |
| RTECS | MI5230000 |
| Hazard Note | Irritant |
| HS Code | 29145000 |
| Hazardous Substances Data | 458-37-7(Hazardous Substances Data) |
| MSDS Information |
| Provider | Language |
|---|---|
| C.I. 75300 | English |
| Curcumin Usage And Synthesis |
| Chemical Properties | orange crystalline powder |
| Usage | A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope. |
| Usage | antiedemic, antiinflammatory, bile stimulant; antibacterial, antifungal, lipo/cyclooxygenase inhibitor |
| Usage | Curcumin is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). The curcuminoids are polyphenols and are responsible for the yellow color of turmeric. Curcumin can exist in at least two t |
| General Description | Orange-yellow needles. |
| Air & Water Reactions | Slightly soluble in hot water . |
| Reactivity Profile | Curcumin is sensitive to light and changes in pH. Curcumin may react with oxidizing materials. |
| Biological Activity | Antitumor, anti-inflammatory and antioxidant agent. Downregulates expression of reactive-oxygen-generating enzymes (cyclooxygenase, lipoxygenase, iNOS), TNF α , IL-1, IL-6, PKC, EGFR, NF- κ B, I κ B kinase and more. Upregulates expression of PPAR γ , p53, Nrf2. Also displays antimicrobial, antidiabetic neuro- and cardioprotective properties in vivo . |
| Curcumin Basic information |
| Product Name: | Curcumin |
| Synonyms: | Curcumin (mixture of curcumin;TURMERIC EXTRACT;1,6-Heptadiene-3,5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)-,(E,E)-;5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)-,(e,e)-6-heptadiene-3;5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)-6-heptadiene-3;6-Heptadiene-3,5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)-,(E,E)-1;curcuma;haidr |
| CAS: | 458-37-7 |
| MF: | C21H20O6 |
| MW: | 368.38 |
| EINECS: | 207-280-5 |
| Product Categories: | Miscellaneous Natural Products;Analytical Chemistry;Antioxidant;Biochemistry;Indicator (pH);pH Indicators;Colorants;Natural Plant Extract;Aromatics;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Diferuloylmethane, Natural Yellow 3, C.I. 75300;pigment |
| Mol File: | 458-37-7.mol |
|
|
|
| Curcumin Chemical Properties |
| mp | 183 °C |
| density | 0.93 |
| vapor density | 13 (vs air) |
| refractive index | 1.4155-1.4175 |
| storage temp. | −20°C |
| solubility | ethanol: 10 mg/mL |
| form | powder |
| Colour Index | 75300 |
| color | orange |
| Water Solubility | Slightly soluble (hot) |
| Merck | 14,2673 |
| BRN | 2306965 |
| Stability: | Stable, but may be light sensitive. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 458-37-7(CAS DataBase Reference) |
| EPA Substance Registry System | 1,6-Heptadiene-3, 5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (1E,6E)-(458-37-7) |
| Safety Information |
| Hazard Codes | Xi,F |
| Risk Statements | 36/37/38-11 |
| Safety Statements | 26-36-16-7 |
| WGK Germany | 2 |
| RTECS | MI5230000 |
| Hazard Note | Irritant |
| HS Code | 29145000 |
| Hazardous Substances Data | 458-37-7(Hazardous Substances Data) |
| MSDS Information |
| Provider | Language |
|---|---|
| C.I. 75300 | English |
| Curcumin Usage And Synthesis |
| Chemical Properties | orange crystalline powder |
| Usage | A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope. |
| Usage | antiedemic, antiinflammatory, bile stimulant; antibacterial, antifungal, lipo/cyclooxygenase inhibitor |
| Usage | Curcumin is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). The curcuminoids are polyphenols and are responsible for the yellow color of turmeric. Curcumin can exist in at least two t |
| General Description | Orange-yellow needles. |
| Air & Water Reactions | Slightly soluble in hot water . |
| Reactivity Profile | Curcumin is sensitive to light and changes in pH. Curcumin may react with oxidizing materials. |
| Biological Activity | Antitumor, anti-inflammatory and antioxidant agent. Downregulates expression of reactive-oxygen-generating enzymes (cyclooxygenase, lipoxygenase, iNOS), TNF α , IL-1, IL-6, PKC, EGFR, NF- κ B, I κ B kinase and more. Upregulates expression of PPAR γ , p53, Nrf2. Also displays antimicrobial, antidiabetic neuro- and cardioprotective properties in vivo . |