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Country: China (Mainland)
Business Type:Trading Company
Tel: +86-371- 86259723
Tel: 17734809689
Tel: 17734809689
Tel: 86-371-86259723
Tel: 17734809689
Tel: 17734809689
Mobile: 17734809689
Tel: +86-371- 86259723
Fax: +86-371- 86259723
Province/state: HENAN
City: ZHENGZHOU
Street: Mingmen International Center, NO.222 Dongming Road,Zhengzhou,Henan,China
MaxCard:
CAS NO.450-76-0
HENAN SUNLAKE ENTERPRISE CORPORATION
Our company advantages:
1. The highest quality with the competitive price.
2. Professional human services.
3. The fastest and safest delivery service.
4. The faster and safest delivery service.
5. The high purity products.
6. We have a sufficient supply of stock.
7. A variety of payments, such as L/C, TT, , MoneyGram or other payments.
Actinomycin D Basic information |
Product Name: | Actinomycin D |
Synonyms: | 1-ethanediyl)imino(2-(1-methylethyl)-carbonylimino(2-(1-hydroxyethyl)-1-oxo-;1-oxo-2,1-ethanediyl)-1,2-pyrrolidinediylcarbonyl(methylimino)(1-oxo-2,1-ethan;3h-phenoxazine-1,9-dicarboxamide,2-amino-n,n’-bis(hexadecahydro-2,5,9-trimethy;6-dimethyl-3-oxo-xatetra-azacyclohexadecin-10-yl)-;actd;actinomycin-(thre-val-pro-sar-meval);actinomycin11cosmegen;actinomycin7 |
CAS: | 50-76-0 |
MF: | C62 H86 N12 O16 |
MW: | 1255.44 |
EINECS: | 232-485-1 |
Product Categories: | Antibiotics;Antibiotic Explorer;Intermediates & Fine Chemicals;Peptides;Pharmaceuticals;Caspases/Apoptosis;COSMEGEN;antibiotic |
Mol File: | 50-76-0.mol |
Actinomycin D Chemical Properties |
Melting point | 251-253 °C |
storage temp. | 2-8°C |
solubility | ethanol, DMSO: Stable in aqueous solutions at 2-8 °C.soluble |
form | powder |
color | red, powder |
Water Solubility | SOLUBLE |
Merck | 13,2828 |
Stability: | Stable, but light sensitive, especially in dilute solution. Incompatible with strong acids, strong bases, strong oxidizing agents. Combustible. |
CAS DataBase Reference | 50-76-0(CAS DataBase Reference) |
EPA Substance Registry System | Actinomycin D(50-76-0) |
Safety Information |
Hazard Codes | T+ |
Risk Statements | 28-61-40-45-26/27/28 |
Safety Statements | 53-36/37/39-45-1-36/37-28-22 |
RIDADR | UN 3462 6.1/PG 2 |
WGK Germany | 3 |
RTECS | AU1575000 |
F | 8-10-21 |
HazardClass | 6.1(a) |
PackingGroup | II |
HS Code | 29419000 |
Hazardous Substances Data | 50-76-0(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
Actinomycin D | English |
SigmaAldrich | English |
Actinomycin D Usage And Synthesis |
Chemical Properties | red crystalline powder |
Usage | An antineoplastic antibiotic that inhibits cell proliferation by forming a stable complex with DNA and blocking the movement of RNA polymerase which interferes with DNA-dependent RNA synthesis. Induces apoptosis. Potent antitumor agent. |
Usage | antineoplastic, intercalating agent |
Usage | Actinomycin D is the most studied member of a family of unique bicyclic depsipeptides produced by several Streptomyces species. The depsipeptides are linked by a heterocyclic benzoxazone "anchor" that gives the metabolites a highly distinctive red/orange colour. Actinomycin D exhibits potent antibiotic and antitumour activity via DNA intercalation leading to the inhibition of nucleic acid synthesis. Tumour cell death has been demonstrated to occur by apoptosis. |
Usage | Actinomycin D is the most studied member of a family of unique bicyclic depsipeptides produced by several Streptomyces species. The depsipeptides are linked by a heterocyclic benzoxazone "anchor" that gives the metabolites a highly distinctive red/orange colour. Actinomycin D exhibits potent antibiotic and antitumor activity via DNA intercalation leading to the inhibition of nucleic acid synthesis. Tumor cell death has been demonstrated to occur by apoptosis. |
Usage | Antibiotic substance belonging to the actinomycin complex, produced by several Streptomyces spp. Antineoplastic |
General Description | Bright red rhomboid prisms or red powder. |
Air & Water Reactions | Water soluble. |
Reactivity Profile | Actinomycin D can react with strong oxidizing agents, strong acids and strong bases. |
Fire Hazard | Flash point data for Actinomycin D are not available. Actinomycin D is probably combustible. |
Biological Activity | Anti-neoplastic antibiotic. Inhibits RNA polymerase and is a potent inducer of apoptosis. |
Actinomycin D Preparation Products And Raw materials |
Raw materials | Aluminum oxide -->streptomyces avermifilis-->Sepia (dye) |
Henan Sunlake Enterprise Corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion. The com[any was established in june. 1998, until now having more than 18 years experience in manufacturing & exporting chemical raw material .
Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs , Water treatment chemicals , Food & FEED additives and others. These products have been being well exported to europe, southeast Asia, the Middle East ,Africa, South America and some other countries and areas.
We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you better with our high - quality products and professional team. We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional supplier in international market.
We welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!