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1-ethanediyl)imino(2-(1-methylethyl)-carbonylimino(2-(1-hydroxyethyl)-1-oxo-

CAS NO.450-76-0

  • Min.Order: 1 Gram
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Product Details

Keywords

  • 1-ethanediyl)imino(2-(1-methylethyl)-carbonylimino(2-(1-hydroxyethyl)-1-oxo-
  • 50-76-0
  • 50-76-0 price

Quick Details

  • ProName: 1-ethanediyl)imino(2-(1-methylethyl)-c...
  • CasNo: 450-76-0
  • Molecular Formula: C62 H86 N12 O16
  • Appearance: red crystalline powder
  • Application: organic synthesis
  • DeliveryTime: Within 7 working days
  • PackAge: 1g,5g,10g...more
  • Port: Shanghai Port
  • ProductionCapacity: 100 Gram/Week
  • Purity: 98% Min
  • Storage: Protected from light, stored hermetica...
  • Transportation: By air
  • LimitNum: 1 Gram
  • Molecular Weight: 1255.44

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Details

Actinomycin D Basic information
Product Name: Actinomycin D
Synonyms: 1-ethanediyl)imino(2-(1-methylethyl)-carbonylimino(2-(1-hydroxyethyl)-1-oxo-;1-oxo-2,1-ethanediyl)-1,2-pyrrolidinediylcarbonyl(methylimino)(1-oxo-2,1-ethan;3h-phenoxazine-1,9-dicarboxamide,2-amino-n,n’-bis(hexadecahydro-2,5,9-trimethy;6-dimethyl-3-oxo-xatetra-azacyclohexadecin-10-yl)-;actd;actinomycin-(thre-val-pro-sar-meval);actinomycin11cosmegen;actinomycin7
CAS: 50-76-0
MF: C62 H86 N12 O16
MW: 1255.44
EINECS: 232-485-1
Product Categories: Antibiotics;Antibiotic Explorer;Intermediates & Fine Chemicals;Peptides;Pharmaceuticals;Caspases/Apoptosis;COSMEGEN;antibiotic
Mol File: 50-76-0.mol
Actinomycin D Structure
 
Actinomycin D Chemical Properties
Melting point  251-253 °C
storage temp.  2-8°C
solubility  ethanol, DMSO: Stable in aqueous solutions at 2-8 °C.soluble
form  powder
color  red, powder
Water Solubility  SOLUBLE
Merck  13,2828
Stability: Stable, but light sensitive, especially in dilute solution. Incompatible with strong acids, strong bases, strong oxidizing agents. Combustible.
CAS DataBase Reference 50-76-0(CAS DataBase Reference)
EPA Substance Registry System Actinomycin D(50-76-0)
 
Safety Information
Hazard Codes  T+
Risk Statements  28-61-40-45-26/27/28
Safety Statements  53-36/37/39-45-1-36/37-28-22
RIDADR  UN 3462 6.1/PG 2
WGK Germany  3
RTECS  AU1575000
8-10-21
HazardClass  6.1(a)
PackingGroup  II
HS Code  29419000
Hazardous Substances Data 50-76-0(Hazardous Substances Data)
MSDS Information
Provider Language
Actinomycin D English
SigmaAldrich English
 
Actinomycin D Usage And Synthesis
Chemical Properties red crystalline powder
Usage An antineoplastic antibiotic that inhibits cell proliferation by forming a stable complex with DNA and blocking the movement of RNA polymerase which interferes with DNA-dependent RNA synthesis. Induces apoptosis. Potent antitumor agent.
Usage antineoplastic, intercalating agent
Usage Actinomycin D is the most studied member of a family of unique bicyclic depsipeptides produced by several Streptomyces species. The depsipeptides are linked by a heterocyclic benzoxazone "anchor" that gives the metabolites a highly distinctive red/orange colour. Actinomycin D exhibits potent antibiotic and antitumour activity via DNA intercalation leading to the inhibition of nucleic acid synthesis. Tumour cell death has been demonstrated to occur by apoptosis.
Usage Actinomycin D is the most studied member of a family of unique bicyclic depsipeptides produced by several Streptomyces species. The depsipeptides are linked by a heterocyclic benzoxazone "anchor" that gives the metabolites a highly distinctive red/orange colour. Actinomycin D exhibits potent antibiotic and antitumor activity via DNA intercalation leading to the inhibition of nucleic acid synthesis. Tumor cell death has been demonstrated to occur by apoptosis.
Usage Antibiotic substance belonging to the actinomycin complex, produced by several Streptomyces spp. Antineoplastic
General Description Bright red rhomboid prisms or red powder.
Air & Water Reactions Water soluble.
Reactivity Profile Actinomycin D can react with strong oxidizing agents, strong acids and strong bases.
Fire Hazard Flash point data for Actinomycin D are not available. Actinomycin D is probably combustible.
Biological Activity Anti-neoplastic antibiotic. Inhibits RNA polymerase and is a potent inducer of apoptosis.
 
Actinomycin D Preparation Products And Raw materials
Raw materials Aluminum oxide -->streptomyces avermifilis-->Sepia (dye)

Company Information

Henan Sunlake Enterprise Corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion. The com[any was established in june. 1998, until now having more than 18 years experience in manufacturing & exporting chemical raw material .

Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs , Water treatment chemicals , Food & FEED additives and others. These products have been being well exported to europe, southeast Asia, the Middle East ,Africa, South America and some other countries and areas.

We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you better with our high - quality products and professional team. We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional supplier in international market.

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