Product Certification&
Enterprise Certification
Country: China (Mainland)
Business Type:Trading Company
Tel: +86-371- 86259723
Tel: 17734809689
Tel: 17734809689
Tel: 86-371-86259723
Tel: 17734809689
Tel: 17734809689
Mobile: 17734809689
Tel: +86-371- 86259723
Fax: +86-371- 86259723
Province/state: HENAN
City: ZHENGZHOU
Street: Mingmen International Center, NO.222 Dongming Road,Zhengzhou,Henan,China
MaxCard:
1.Certificate Of Analysis (COA)
2.Material Safety Data Sheet (MSDS)
3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)
About Service
1. Quality control, before shipment, free sample for test.
2. Prompt shipment with professional documents
3. Packing as your request, with photo before shipment
4. Mixed containers with different mixed items in one container
About Company
Product Name: | Azathioprine |
Synonyms: | 6-((1-methyl-4-nitro-1h-imidazol-5-yl)thio)-1h-purin;6-((1-methyl-4-nitroimidazol-5-yl)thio)-purin;6-(1’-methyl-4’-nitro-5’-imidazolyl)-mercaptopurine;6-(1-Methyl-4-nitro-5-imidazolythio)-9H-pur-ine;6-(1-methyl-4-nitroimidazol-5-ylthio)purin;6-(1-methyl-p-nitro-5-imidazolyl)-thiopurine;azamun;azanin |
CAS: | 446-86-6 |
MF: | C9H7N7O2S |
MW: | 277.27 |
EINECS: | 207-175-4 |
Product Categories: | Sulphur Derivatives;Purine;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleobases and their analogs;Nucleosides, Nucleotides & Related Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Miscellaneous Compounds;AZANIN;Pharmaceutical intermediates |
Mol File: | 446-86-6.mol |
Azathioprine Chemical Properties |
mp | 243-244°C |
storage temp. | Freezer |
Water Solubility | <0.1 g/100 mL at 23 ºC |
Merck | 902 |
Stability: | Stable. Incompatible with strong oxidizing agents, strong bases. |
CAS DataBase Reference | 446-86-6(CAS DataBase Reference) |
EPA Substance Registry System | 1H-Purine, 6-[(1-methyl-4-nitro-1H-imidazol- 5-yl)thio]-(446-86-6) |
Safety Information |
Hazard Codes | Xi,T,Xn |
Risk Statements | 45-22-36/37/38-20/21/22 |
Safety Statements | 53-22-26-36/37-45-36 |
RTECS | UO8925000 |
Hazard Note | Irritant |
HazardClass | IRRITANT |
Hazardous Substances Data | 446-86-6(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
Azathioprine | English |
Azathioprine Usage And Synthesis |
Chemical Properties | Yellow Solid |
Usage | immunosuppressant, antineoplastic, antirheumatic |
Usage | An immunosuppressive antimetabolite. Also active as disease modifying antirheumatic drug (DMARD). Azathioprine is a purine analog with immunosuppressive effects. |
General Description | Pale yellow crystals or yellowish powder. Decomposes at 243-244°C. Used for the treatment of rheumatoid arthritis. A known carcinogen. |
Air & Water Reactions | Sensitive to oxidation in the air. Insoluble in water. |
Reactivity Profile | Azathioprine may react exothermically with acids. Incompatible with isocyanates, peroxides, phenols, epoxides, anhydrides, and acid halides. Hydrolyzed by strongly basic solutions . May react with strong reducing agents to generate flammable gaseous hydrogen or hydrogen sulfide. |
Fire Hazard | Flash point data for Azathioprine are not available. Azathioprine is probably combustible. |
Azathioprine Preparation Products And Raw materials |
Raw materials | Diethyl oxalate-->Phosphorus pentachloride-->Dimethylamine-->6-Mercaptopurine -->5-Chloro-1-methyl-4-nitroimidazole-->5-Chloro-1-methylimidazole |