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BIBW 2992 439081-18-2

CAS NO.439081-18-2

  • FOB Price: USD: /Metric Ton Get Latest Price
  • Min.Order: 100 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,Other
  • Available Specifications:

    1(10-100)Metric Ton1(10-100)Metric Ton

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Product Details

Keywords

  • RARECHEM AH PB 0251
  • 439081-18-2
  • C24H25ClFN5O3

Quick Details

  • ProName: BIBW 2992 439081-18-2
  • CasNo: 439081-18-2
  • Molecular Formula: C24H25ClFN5O3
  • Appearance: powder
  • Application: 439081-18-2
  • DeliveryTime: Within 3-7 days
  • PackAge: Depended
  • Port: China Main Port
  • ProductionCapacity: 300 Kilogram/Month
  • Purity: 99%
  • Storage: Refrigerator
  • Transportation: by air or by sea
  • LimitNum: 100 Kilogram
  • Valid Period: 6 month
  • Application: Multipurpose intermediate
  • Application: ISO/9001 Certificate

Superiority

BIBW 2992 Basic information
Product Name: BIBW 2992
Synonyms: BIBW 2992;N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide;Tovok;Tovok, BIBW 2992;BIBW2992 Afatinib;Afatinib (BIBW 2992);ToMtovok;(S,E)-N-(4-(3-chloro-4-fluorophenylaMino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(diMethylaMino)but-2-enaMide
CAS: 439081-18-2
MF: C24H25ClFN5O3
MW: 485.944
EINECS:  
Product Categories: API;Inhibitors
Mol File: 439081-18-2.mol
BIBW 2992 Structure
 
BIBW 2992 Chemical Properties
density  1.380
 
Safety Information
MSDS Information
 
 
BIBW 2992 Usage And Synthesis
Usage BIBW2992 (Afatinib, Tomtovok, Tovok) irreversibly inhibits EGFR/HER2 including EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively.
 
 

 

 

 

 

 

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