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CAS NO.396-01-0
| 2,4,7-Triamino-6-phenylpteridine Basic information |
| Product Name: | 2,4,7-Triamino-6-phenylpteridine |
| Synonyms: | 6-PHENYL-PTERIDINE-2,4,7-TRIAMINE;6-PHENYL-2,4,7-PTERIDINETRIAMINE;6-PHENYL-2,4,7-TRIAMINO PTERIDINE;ADEMINE;2,4,7-TRIAMINO-6-PHENYLPTERIDINE;TRIAMTERENE;2,4,7-triamino-6-fenilpteridina;2,4,7-triamino-6-phenyl-pteridin |
| CAS: | 396-01-0 |
| MF: | C12H11N7 |
| MW: | 253.26 |
| EINECS: | 206-904-3 |
| Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Ion transporter and other ion channel;Aromatics;Bases & Related Reagents;Nucleotides;DYRENIUM;Other APIs |
| Mol File: | 396-01-0.mol |
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| 2,4,7-Triamino-6-phenylpteridine Chemical Properties |
| Melting point | 316°C |
| Fp | 11 °C |
| storage temp. | 2-8°C |
| Water Solubility | <0.1 G/100 ML AT 20 ºC |
| Merck | 14,9599 |
| BRN | 266723 |
| CAS DataBase Reference | 396-01-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Triamterene(396-01-0) |
| EPA Substance Registry System | 2,4,7-Pteridinetriamine, 6-phenyl-(396-01-0) |
| Safety Information |
| Hazard Codes | Xn,T,F |
| Risk Statements | 22-36/37/38-36/38-23/25-39/23/24/25-23/24/25-11 |
| Safety Statements | 26-36/37/39-45-33-24-16-7-36/37 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| RTECS | UO3470000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Hazardous Substances Data | 396-01-0(Hazardous Substances Data) |
| MSDS Information |
| Provider | Language |
|---|---|
| 2,4,7-Triamino-6-phenylpteridine | English |
| SigmaAldrich | English |
| ALFA | English |
| 2,4,7-Triamino-6-phenylpteridine Usage And Synthesis |
| Chemical Properties | Yellow Solid |
| Usage | Triamterene is a potassium-sparing diuretic ie, it inhibits the urinary excretion of potassium |
| Usage | Triamterene is a weak diuretic with potassium sparing properties; blocks Na+ reuptake in the kidneys. |
| General Description | Odorless yellow powder or crystalline solid. Melting point 316°C. Almost tasteless at first and with a slightly bitter aftertaste. Acidified solutions give a blue fluorescence. Used as a diuretic drug. |
| Air & Water Reactions | Sensitive to light; slowly oxidized upon exposure to air. Insoluble in water. |
| Reactivity Profile | 2,4,7-Triamino-6-phenylpteridine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. |
| Fire Hazard | Flash point data for 2,4,7-Triamino-6-phenylpteridine are not available; however, 2,4,7-Triamino-6-phenylpteridine is probably combustible. |
| 2,4,7-Triamino-6-phenylpteridine Preparation Products And Raw materials |
| Raw materials | Ethyl cyanoacetate-->Sodium ethoxide-->Disodium edetate dihydrate-->phenylacetonitrile-->2,4,6-Triaminopyrimidine |
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