HENAN SUNLAKE ENTERPRISE CORPORATION
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Tel: +86-371- 86259723
Tel: 17734809689
Tel: 17734809689
Tel: 86-371-86259723
Tel: 17734809689
Tel: 17734809689
Mobile: 17734809689
Tel: +86-371- 86259723
Fax: +86-371- 86259723
Province/state: HENAN
City: ZHENGZHOU
Street: Mingmen International Center, NO.222 Dongming Road,Zhengzhou,Henan,China
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CAS NO.38183-03-8
| 7,8-DIHYDROXYFLAVONE Basic information |
| Product Name: | 7,8-DIHYDROXYFLAVONE |
| Synonyms: | 7,8-dihydroxy-2-phenyl-4h-1-benzopyran-4-on;TIMTEC-BB SBB000930;DIHYDROXYFLAVONE, 7,8-;7,8-DIHYDROXYFLAVONE;7,8-dihydroxy-2-phenyl-4-benzopyrone;DIHYDROXYFLAVONE, 7,8-(RG);7,8-Dihydroxyflavone hydrate;2-Phenyl-7,8-dihydroxy-4H-1-benzopyran-4-one |
| CAS: | 38183-03-8 |
| MF: | C15H10O4 |
| MW: | 254.24 |
| EINECS: | 253-812-4 |
| Product Categories: | Di-substituted Flavones;Biochemistry;Flavonoids;Inhibitors |
| Mol File: | 38183-03-8.mol |
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| 7,8-DIHYDROXYFLAVONE Chemical Properties |
| mp | 243-246°C |
| storage temp. | Store at +4°C |
| CAS DataBase Reference | 38183-03-8(CAS DataBase Reference) |
| 7,8-DIHYDROXYFLAVONE Usage And Synthesis |
| Chemical Properties | Yellow Solid |
| Usage | 7,8-Dihydroxyflavone is disubstituted flavone that acts as a small-molecule TrkB agonist. 7,8-Dihydroxyflavone has been shown to reverse memory deficits and BACE1 elevation in a mouse model of Alzheim er's disease. 7,8-Dihydroxyflavone may also provide a therapeutic option in the treatment of other neorological disorders such as Rett syndrome and PTSD. |
| Usage | vascular protectant, antihaemorrhagic, tyr kinase B agonist |
| Biological Activity | Tyrosine kinase receptor B (TrkB) agonist that binds to the extracellular domain of the receptor (K d = 320 nM). Inhibits glutamate-triggered apoptosis in hippocampal neurons in vitro and in vivo . |
| Product Name: | 7,8-DIHYDROXYFLAVONE |
| Synonyms: | 7,8-dihydroxy-2-phenyl-4h-1-benzopyran-4-on;TIMTEC-BB SBB000930;DIHYDROXYFLAVONE, 7,8-;7,8-DIHYDROXYFLAVONE;7,8-dihydroxy-2-phenyl-4-benzopyrone;DIHYDROXYFLAVONE, 7,8-(RG);7,8-Dihydroxyflavone hydrate;2-Phenyl-7,8-dihydroxy-4H-1-benzopyran-4-one |
| CAS: | 38183-03-8 |
| MF: | C15H10O4 |
| MW: | 254.24 |
| EINECS: | 253-812-4 |
| Product Categories: | Di-substituted Flavones;Biochemistry;Flavonoids;Inhibitors |
| Mol File: | 38183-03-8.mol |
| Chemical Properties | Yellow Solid |
| Usage | 7,8-Dihydroxyflavone is disubstituted flavone that acts as a small-molecule TrkB agonist. 7,8-Dihydroxyflavone has been shown to reverse memory deficits and BACE1 elevation in a mouse model of Alzheim er's disease. 7,8-Dihydroxyflavone may also provide a therapeutic option in the treatment of other neorological disorders such as Rett syndrome and PTSD. |
| Usage | vascular protectant, antihaemorrhagic, tyr kinase B agonist |
| Biological Activity | Tyrosine kinase receptor B (TrkB) agonist that binds to the extracellular domain of the receptor (K d = 320 nM). Inhibits glutamate-triggered apoptosis in hippocampal neurons in vitro and in vivo . |
Henan Sunlake Enterprise Corporation , facing global High-tech pharmaceutical raw materials, high value-added new type intermediates fine chemicals custom synthesis, scale-up production and rare chemicals trade. We have experienced research staff, strong technical force, well-equipped machine, and considerate marketing team service, with a strict customer intellectual property security system, we are already become good partner of customers from difficult and complex chemical and biological chemical field. Our high quality & low price and effective services shortened new product development cycle,reduced the development and production cost for numerous partners.
The company has completed numerous domestic and overseas famous pharmaceutical, chemical, biological and other large and medium-sized company R&D outsourcing services, synthesis process development and optimization services, chemical intermediates customized service, special chemical processing and production services, etc., We hope to become continuous mutually beneficial partnership with you, to create a better business opportunities together.
Service Scope:
1. Samples synthetic, Our strong r&d team has accumulated abundant experience in synthesis design and exploring synthesis of new technology. Not only good at heterocyclic chemistry, chiral chemicals (asymmetric synthesis and enzyme reaction), metal organic synthesis, high throughput chemistry, also specializes in bioorganic chemistry including nucleosides, nucleotides, sugar chemical, peptide chemistry, etc, to complete the synthesis from mg to kg samples in lab scale. Our efficient management and good communication skills and ability to solve the problem rapidly in order to ensure quality, timely delivery, based on the standard client confidential system and competitive price products,we has been recognized and praised by many customers in chemical industry.
2. Scale-up production, based on our rich laboratory experience and advanced equipment in production base, also depend on accumulation of advantages in many aspects as industrialized technology development, the production cost control, to provide from kg class to wt class custom synthesis scale-up production services to the global fine chemical industry, can be carried out oxidation, hydrogenation pressure (70 kg), halide, and acylation, esterification, condensation, cyclization, formatting, ammoniation, diazotization and azide reaction, our experienced production management, strict and perfect management system can quickly provide customers with competitive and fine mass production services.
3.Technology transfer, the company has accumulated a large number of production processes of drugs, intermediates and raw material. Based on the principle of mutual benefit, and some technology transfer to industry manufacturers, also provides them marketing support.
4. Purchasing agency service, Our excellence professional sales team, timely and thoughtful service, in addition to the necessary good language communication ability of professional sales staff, also equipped with professional chemical technical sales consultant, who can answer the customer's academic professional question, we are in line with the aim of offering customer wholehearted service, with our advanced testing equipment checks and abundant R&D and production of domestic partner contacts, to provide rare chemicals with standard purity, reasonable price and cost-effective purchasing agency service to foreign customers, and the help you shorten the sourcing time, reduce the purchasing cost.
