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CAS NO.38183-03-8
1. Certificate Of Analysis (COA)
2. Material Safety Data Sheet (MSDS)
3. Route of synthesis (ROS)
4. Method of Aanlysis (MOA)
5. Nuclear Magnetic Resonance (NMR)
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Chemical name |
7,8-dihydroxyflavone |
CAS No. |
38183-03-8 |
Synonym |
7,8-DHF |
Molecular Formula |
C15H10O4 |
Molecular Weight |
|
Store at |
Room temperature |
Purity |
99% min |
Appearance |
White to off white powder |
7,8-DIHYDROXYFLAVONE Basic information |
Product Name: | 7,8-DIHYDROXYFLAVONE |
Synonyms: | 7,8-dihydroxy-2-phenyl-4h-1-benzopyran-4-on;TIMTEC-BB SBB000930;DIHYDROXYFLAVONE, 7,8-;7,8-DIHYDROXYFLAVONE;7,8-dihydroxy-2-phenyl-4-benzopyrone;DIHYDROXYFLAVONE, 7,8-(RG);7,8-Dihydroxyflavone hydrate;2-Phenyl-7,8-dihydroxy-4H-1-benzopyran-4-one |
CAS: | 38183-03-8 |
MF: | C15H10O4 |
MW: | 254.24 |
EINECS: | 253-812-4 |
Product Categories: | Di-substituted Flavones;Biochemistry;Flavonoids;Inhibitors |
Mol File: | 38183-03-8.mol |
7,8-DIHYDROXYFLAVONE Chemical Properties |
mp | 243-246°C |
storage temp. | Store at +4°C |
CAS DataBase Reference | 38183-03-8(CAS DataBase Reference) |
7,8-DIHYDROXYFLAVONE Usage And Synthesis |
Chemical Properties | Yellow Solid |
Usage | 7,8-Dihydroxyflavone is disubstituted flavone that acts as a small-molecule TrkB agonist. 7,8-Dihydroxyflavone has been shown to reverse memory deficits and BACE1 elevation in a mouse model of Alzheim er's disease. 7,8-Dihydroxyflavone may also provide a therapeutic option in the treatment of other neorological disorders such as Rett syndrome and PTSD. |
Usage | vascular protectant, antihaemorrhagic, tyr kinase B agonist |
Biological Activity | Tyrosine kinase receptor B (TrkB) agonist that binds to the extracellular domain of the receptor (K d = 320 nM). Inhibits glutamate-triggered apoptosis in hippocampal neurons in vitro and in vivo . |
7,8-DIHYDROXYFLAVONE Preparation Products And Raw materials |