Keywords

• 5-Azacytidine
• 320-67-2
• C8H12N4O5

Quick Details

• ProName: 5-Azacytidine 320-67-2 C8H12N4O5
• CasNo: 320-67-2
• Molecular Formula: C8H12N4O5
• Appearance: detailed in specifcations
• Application: Aripiprazole Intermediate functional...
• DeliveryTime: within 5days
• PackAge: as needed
• Port: China main port
• ProductionCapacity: 500 Metric Ton/Month
• Purity: 99%
• Storage: Keep in dry and cool condition
• Transportation: by air or sea
• LimitNum: 1 Kilogram
• MF: C13H21O3PS

Superiority

Our Services

1.Certificate Of Analysis (COA)

2.Material Safety Data Sheet (MSDS)

3.Route of synthesis (ROS)

4.Method of Aanlysis (MOA)

5.Nuclear Magnetic Resonance (NMR)

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Company information

Henan Sunlake Enterprise Corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs , Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East , Africa , South America and some other countries and areas.We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you better with our high - quality products and professional team.We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.We welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate.

Details

5-Azacytidine Basic information

Product Name:	5-Azacytidine
Synonyms:	4-amino-1-beta-d-ribofuranosyl-s-triazin-2(1h)-on;5-triazin-2(1h)-one,4-amino-1-beta-d-ribofuranosyl-3;antibioticu18496;mylosar;nci-c01569;nsc-102816;u18496;5-AZAC
CAS:	320-67-2
MF:	C8H12N4O5
MW:	244.2
EINECS:	206-280-2
Product Categories:	API intermediates;Antitumors for Research and Experimental Use;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Bases & Related Reagents;Nucleotides;Carbohydrates & Derivatives;Epigenetics;Pyrimidine purine;5-azacytidine, Mylosar, Ladakamycin;CORVATON;Inhibitors
Mol File:	320-67-2.mol

5-Azacytidine Chemical Properties

mp	226-232 °C (dec.)(lit.)
alpha	40 º (C=1, H2O 22 ºC)
storage temp.	2-8°C
form	lyophilized powder
Water Solubility	0.5-1.0 g/100 mL at 21 ºC
Merck	887
CAS DataBase Reference	320-67-2(CAS DataBase Reference)
EPA Substance Registry System	1,3,5-Triazin-2( 1H)-one, 4-amino-1-.beta.-D-ribofuranosyl- (320-67-2)

Safety Information

Hazard Codes	T
Risk Statements	45-46-22
Safety Statements	53-22-36/37/39-45
WGK Germany	3
RTECS	XZ3017500
F	10-23
Hazardous Substances Data	320-67-2(Hazardous Substances Data)

MSDS Information

Provider	Language
5-Azacytidine	English
ACROS	English
SigmaAldrich	English

5-Azacytidine Usage And Synthesis

Chemical Properties	White-to-Off-White Crystalline Solid
Usage	A potent growth inhibitor and cytotoxic agent. It acts as a demethylating agent by inhibiting DNA methyltransferase
Usage	Antineoplastic;'Antimetabolite
Usage	antianginal
General Description	White crystalline powder.
Air & Water Reactions	Slightly water soluble. Unstable in solution.
Reactivity Profile	5-Azacytidine is sensitive to light (may discolor). 5-Azacytidine is sensitive to oxidation. 5-Azacytidine is unstable in solution. 5-Azacytidine undergoes hydrolysis in aqueous buffers. 5-Azacytidine is incompatible with strong oxidizers.
Fire Hazard	Flash point data for 5-Azacytidine are not available; however, 5-Azacytidine is probably combustible.
Biological Activity	DNA methyltransferase inhibitor. Incorporates into DNA forming covalent adducts with cellular DNMT1, depleting enzyme activity. Induces demethylation and reactivation of silenced genes. Improves the efficiency of reprogramming of stem cells.

5-Azacytidine Preparation Products And Raw materials