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CAS NO.2766-74-7
5-Chlorothiophene-2-sulfonyl chloride Basic information |
Product Name: | 5-Chlorothiophene-2-sulfonyl chloride |
Synonyms: | TIMTEC-BB SBB003378;5-CHLORO-2-THIENYLSULFONYL CHLORIDE;5-CHLORO-2-THIOPHENESULFONYL CHLORIDE;5-CHLOROTHIOPHENE-2-SULFONYL CHLORIDE;5-CHLOROTHIOPHENE-2-SULPHONYL CHLORIDE;5-CHLOROTHIOPHENESULPHONYL CHLORIDE;AKOS B019398;ART-CHEM-BB B019398 |
CAS: | 2766-74-7 |
MF: | C4H2Cl2O2S2 |
MW: | 217.09 |
EINECS: | |
Product Categories: | Heterocycles;Thiophene&Benzothiophene;Thiophene intermediates;Halogenated Heterocycles;Heterocyclic Building Blocks;Thiophenes;ThiophenesBuilding Blocks;Building Blocks;C4 to C6;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;Heterocycle-oher series |
Mol File: | 2766-74-7.mol |
5-Chlorothiophene-2-sulfonyl chloride Chemical Properties |
mp | 25-28°C |
bp | 112-117 °C(lit.) |
density | 1.623 g/mL at 25 °C(lit.) |
refractive index |
n |
Fp | >230 °F |
storage temp. | Keep Cold |
Sensitive | Moisture Sensitive |
BRN | 130710 |
CAS DataBase Reference | 2766-74-7(CAS DataBase Reference) |
Safety Information |
Hazard Codes | C |
Risk Statements | 34-29-14 |
Safety Statements | 26-27-36/37/39-45-28A-25 |
RIDADR | UN 3265 8/PG 2 |
WGK Germany | 3 |
Hazard Note | Corrosive |
HazardClass | 8 |
PackingGroup | II |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
ACROS | English |
ALFA | English |
5-Chlorothiophene-2-sulfonyl chloride Usage And Synthesis |
Chemical Properties | white to yellow crystalline low melting solid |
Usage | 5-Chloro-2-thiophenesulfonyl Chloride is a sulfonylthiophene derivative used in the preparation of Notch-1-sparing γ-secretase inhibitors for the treatment of Alzheimer's disease. |
5-Chlorothiophene-2-sulfonyl chloride Preparation Products And Raw materials |
Raw materials | Diethyl ether-->Phosphorus pentachloride-->Chlorosulfonic acid-->2-Chlorothiophene |