HENAN SUNLAKE ENTERPRISE CORPORATION
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Street: Mingmen International Center, NO.222 Dongming Road,Zhengzhou,Henan,China
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CAS NO.21411-53-0
| VIRGINIAMYCIN M1 Basic information |
| Product Name: | VIRGINIAMYCIN M1 |
| Synonyms: | MIKAMYCIN A;STAPHYLOMYCIN;VIRGINIAMYCINE;VIRGINIAMYCIN M1;C11299;MikamycinA, Staphylomycin;Antibiotic PA-114A1;Pristinamycin IIA |
| CAS: | 21411-53-0 |
| MF: | C28H35N3O7 |
| MW: | 525.59 |
| EINECS: | 244-376-6 |
| Product Categories: | Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;antibiotic |
| Mol File: | 21411-53-0.mol |
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| VIRGINIAMYCIN M1 Chemical Properties |
| Melting point | 165-167℃ |
| storage temp. | 2-8°C |
| Safety Information |
| WGK Germany | 3 |
| VIRGINIAMYCIN M1 Usage And Synthesis |
| Chemical Properties | Light yellow powder |
| Usage | Ostreogrycin A (virginiamycin M1, streptogramin A) is the major component of the virginamycin complex. In the 1950s this complex was independently discovered so many times that the literature became highly confusing. Ostreogrycin A is a macrocyclic lactone antibiotic that acts synergistically with the structurally unrelated cyclic depsipeptides, virginiamycin B (ostreogrycin B, streptogramin B) and virginiamycin S, to inhibit peptide elongation. This is achieved by blocking formation of a peptide bond between the growing peptide chain (peptidyl-tRNA) linked to the 50S ribosome and aminoacyl-tRNA. Ostreogrycin A is highly active against Gram positive bacteria, particularly MRSA. |
| Usage | Ostreogrycin A (virginiamycin M1, streptogramin A) is the major component of the virginiamycin complex. In the 1950s this complex was independently discovered so many times that the literature became highly confusing. Ostreogrycin A is a macrocyclic lactone antibiotic that acts synergistically with the structurally unrelated cyclic depsipeptides, virginiamycin B (ostreogrycin B, streptogramin B) and virginiamycin S, to inhibit peptide elongation. This is achieved by blocking formation of a peptide bond between the growing peptide chain (peptidyl-tRNA) linked to the 50S ribosome and aminoacyl-tRNA. Ostreogrycin A is highly active against Gram positive bacteria, particularly MRSA. |
| Usage | Macrolactone antibiotic. Antibacterial; growth promotant. |
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