Keywords

• Capecitabine
• 154361-50-9
• C15H22FN3O6

Quick Details

• ProName: Capecitabine 154361-50-9
• CasNo: 154361-50-9
• Molecular Formula: C15H22FN3O6
• Appearance: detailed in specifcations
• Application: Aripiprazole Intermediate
• DeliveryTime: within 5days
• PackAge: as needed
• Port: China main port
• ProductionCapacity: 500 Metric Ton/Month
• Purity: 99%
• Storage: Keep in dry and cool condition
• Transportation: by air or sea
• LimitNum: 1 Kilogram
• MF: C13H21O3PS

Superiority

Our Services

1.Certificate Of Analysis (COA)

2.Material Safety Data Sheet (MSDS)

3.Route of synthesis (ROS)

4.Method of Aanlysis (MOA)

5.Nuclear Magnetic Resonance (NMR)

6.Packing pictures and loading video before loading

7.Free Sample

9.Factory audit

10.Strong after-sale service

Company information

Henan Sunlake Enterprise Corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs , Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East , Africa , South America and some other countries and areas.We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you better with our high - quality products and professional team.We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.We welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate.

Details

Capecitabine Basic information

Product Description Novel Oral Fluoride Pyrimidine Drugs Tegafur Gimeracil Oteracil Interactions Adverse reaction and attentions Overdose Application

Product Name:	Capecitabine
Synonyms:	5'-DEOXY-5-FLUOROCYTISINE;5'-DEOXY-5-FLUORO-N-[(PENTYLOXY)CARBONYL]CYTIDINE;CAPECITABINE;RO-9-1978;pentyl [1-(3,4-dihydroxy-5-methyl-oxolan-2-yl)-5-fluoro-2-oxo-pyrimidin-4-yl]aminoformate;XELODA;Cpecitabine;5Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine, Ro-9-1978, Xeloda
CAS:	154361-50-9
MF:	C15H22FN3O6
MW:	359.35
EINECS:
Product Categories:	Active Pharmaceutical Ingredients;Antineoplastic;Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Antineoplastic drug, 5-FU analog;Anti-cancer;API;XELODA;Cardiovascular Drugs;Inhibitors
Mol File:	154361-50-9.mol

Capecitabine Chemical Properties

mp	110-121°C
storage temp.	-20°C Freezer
CAS DataBase Reference	154361-50-9(CAS DataBase Reference)

Safety Information

Hazard Codes	T
Risk Statements	45-60-61-68
Safety Statements	53-22-36/37-45
Hazardous Substances Data	154361-50-9(Hazardous Substances Data)

MSDS Information

Provider	Language
Capecitabine	English

Capecitabine Usage And Synthesis

Product Description

Capecitabine, developed by Roche Company and named as Rhoda, is a kind of fluorine pyrimidine carbamate deoxyuridine drug that can transform into 5 - FU in the body and inhibit cell division and disturb the synthesis of RNA and protein. Capecitabine applies to the further treatment of advanced primary or metastatic breast cancer that failed to respond to the paclitaxel or other chemotherapy regimens including anthracycline antibiotics. Its main usage is treating advanced primary or metastatic breast cancer, rectal cancer, colon cancer and stomach cancer. The above information is edited by ChemicalBook Liu Jingjing.

Novel Oral Fluoride Pyrimidine Drugs

As a novel oral fluoride pyrimidine drug, Capecitabine interacts with tumor cells by transforming to 5-FU in a three-step polymerase chain reaction. Its curative effect obviously correlates with the expression level of TP and DPD enzymes of tumor tissues. The high expression level of TP in tumor tissues induces the drug gradient difference between tumor tissues and normal tissues thus achieving relatively selective tumor destruction effect. Animal experiments demonstrate that many drugs such as Taxanes (paclitaxel, docetaxel, mitomycin, cis-platinum etc.) can increase the expression level of TP enzyme, thus enhancing the anti-tumor effect of Capecitabine; and th