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CAS NO.154039-60-8
Marimastat Basic information |
Product Name: | Marimastat |
Synonyms: | Marimastat;(2R,3S)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-N4,3-dihydroxy-2-isobutylsuccinamide;(2S,3R)-N4-[(1S)-2,2-Dimethyl-1-[(methylamino)carbonyl]propyl]-N1,2-dihydroxy-3-(2-methylpropyl)butanediamide;(2R,3S)-N1-((S)-3,3-diMethyl-1-(MethylaMino)-1-oxobutan-2-yl)-N4;BB 2516;GI 5712;KB-R 8898;TA 2516 |
CAS: | 154039-60-8 |
MF: | C15H29N3O5 |
MW: | 331.41 |
EINECS: | |
Product Categories: | |
Mol File: | 154039-60-8.mol |
Marimastat Chemical Properties |
storage temp. | Store at -20°C |
Safety Information |
Marimastat Usage And Synthesis |
Biological Activity | Broad spectrum inhibitor of matrix metalloprotease (MMP) (IC 50 values are 3, 5, 6, 9 and 13 nM for MMP-9, MMP-1, MMP-2, MMP-14 and MMP-7 respectively). In vivo inhibits peritoneal dissemination of human gastric cancer cells through inhibition of tumor angiogenesis. |
Marimastat Basic information |
Product Name: | Marimastat |
Synonyms: | Marimastat;(2R,3S)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-N4,3-dihydroxy-2-isobutylsuccinamide;(2S,3R)-N4-[(1S)-2,2-Dimethyl-1-[(methylamino)carbonyl]propyl]-N1,2-dihydroxy-3-(2-methylpropyl)butanediamide;(2R,3S)-N1-((S)-3,3-diMethyl-1-(MethylaMino)-1-oxobutan-2-yl)-N4;BB 2516;GI 5712;KB-R 8898;TA 2516 |
CAS: | 154039-60-8 |
MF: | C15H29N3O5 |
MW: | 331.41 |
EINECS: | |
Product Categories: | |
Mol File: | 154039-60-8.mol |
Marimastat Chemical Properties |
storage temp. | Store at -20°C |
Safety Information |
Marimastat Usage And Synthesis |
Biological Activity | Broad spectrum inhibitor of matrix metalloprotease (MMP) (IC 50 values are 3, 5, 6, 9 and 13 nM for MMP-9, MMP-1, MMP-2, MMP-14 and MMP-7 respectively). In vivo inhibits peritoneal dissemination of human gastric cancer cells through inhibition of tumor angiogenesis. |