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CAS NO.148553-50-8
| Pregabalin Basic information |
| Antiepileptic drus and therapeutic drugs for neuropathic pain Application |
| Product Name: | Pregabalin |
| Synonyms: | 3(S)-(AMINOMETHYL)-5-METHYLHEXANOIC ACID;(3S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID;PREGABALIN;Pregablin;3-(Aminomethyl)-5-methyl-hexanoic acid;PREDNISOLONESODIUMPHOSPHATE;(R)-Pregabalin;(S)-Pregabalin |
| CAS: | 148553-50-8 |
| MF: | C8H17NO2 |
| MW: | 159.23 |
| EINECS: | 200-659-6 |
| Product Categories: | APIs;Miscellaneous Biochemicals;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals;API;Pfizer compounds;LYRICA |
| Mol File: | 148553-50-8.mol |
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| Pregabalin Chemical Properties |
| mp | 194-196°C |
| storage temp. | Store at RT |
| CAS DataBase Reference | 148553-50-8(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xn,T,F |
| Risk Statements | 63-48/22-39/23/24/25-23/24/25-11 |
| Safety Statements | 22-36/37-45-16-7 |
| Hazardous Substances Data | 148553-50-8(Hazardous Substances Data) |
| Pregabalin Usage And Synthesis |
| Antiepileptic drus and therapeutic drugs for neuropathic pain |
Pregabalin is a new antiepileptic drug, having a γ-amino butyric acid structure on its molecular structure, which has anticonvulsant effects, and is successfully developed by the company Pfizer for the treatment of peripheral neuropathic pain, or adjuvant treatment of partial seizures. In December 2008, the US Food and Drug Administration (FDA) approved pregabalin (trade name "Lyrica") for the treatment of diabetic peripheral neuropathic pain (DPN) and postherpetic neuralgia (PHN)which are Both the most common neuropathic pains. Neuropathic pain is one of the most difficult chronic pain syndromes to treat , dull pain, burning, tingling as the main feature, there are a lot of incentives of neuralgia, diabetes, infections (such as herpes zoster), cancer and AIDS, etc. can cause neurological pain, in Europe about 3% of the population suffer from neuralgia torture. The above information is edited by the chemicalbook of Tian Ye. |
| Application | new antiepileptic drugs |
| Chemical Properties | Off-White Solid |
| Usage | S-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia. |
| Usage | Pregabalin is an anticonvulsant drug used for neuropathic pain, as an adjunct therapy for partial seizures, and in generalized anxiety disorder. It was designed as a more potent successor to gabapentin. Pregabalin is marketed by Pfizer under the trade nam |
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