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Country: China (Mainland)
Business Type:Trading Company
Tel: +86-371- 86259723
Tel: 17734809689
Tel: 17734809689
Tel: 86-371-86259723
Tel: 17734809689
Tel: 17734809689
Mobile: 17734809689
Tel: +86-371- 86259723
Fax: +86-371- 86259723
Province/state: HENAN
City: ZHENGZHOU
Street: Mingmen International Center, NO.222 Dongming Road,Zhengzhou,Henan,China
MaxCard:
CAS NO.143-67-9
1.Certificate Of Analysis (COA)
2.Material Safety Data Sheet (MSDS)
3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)
About Service
1. Quality control, before shipment, free sample for test.
2. Prompt shipment with professional documents
3. Packing as your request, with photo before shipment
4. Mixed containers with different mixed items in one container
About Company
Product Name: | Vinblastine sulfate |
Synonyms: | 29060le;exal;nsc49842;rozevinsulfate;velban;velbe;vincaleukoblastine,sulfate(1:1)(salt);VINBLASTINE SULFATE SALT |
CAS: | 143-67-9 |
MF: | C46H60N4O13S |
MW: | 909.05 |
EINECS: | 205-606-0 |
Product Categories: | Active Pharmaceutical Ingredients;APIs;VINBLASTINE SULPHATE;Intermediates & Fine Chemicals;Pharmaceuticals;Caspases/Apoptosis;Chiral Reagents;Heterocycles;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;VELBAN;Antineoplastic;Anti-cancer & immunity;Inhibitors |
Mol File: | 143-67-9.mol |
Vinblastine sulfate Chemical Properties |
mp | 267 °C (dec.)(lit.) |
alpha | -21.7 º (c=2, CH3OH 21 ºC) |
storage temp. | 2-8°C |
solubility | H2O: 10 mg/mL |
form | powder |
color | white |
Water Solubility | >=1 g/100 mL at 24.5 ºC |
Merck | 13,10044 |
CAS DataBase Reference | 143-67-9(CAS DataBase Reference) |
EPA Substance Registry System | Vincaleukoblastine, sulfate (1:1) (salt)(143-67-9) |
Safety Information |
Hazard Codes | Xn,T |
Risk Statements | 22-37/38-41-61-36/37/38-63-23/24/25 |
Safety Statements | 26-36/39-53-45-37/39-36/37/39 |
RIDADR | 1544 |
WGK Germany | 3 |
RTECS | YY8400000 |
F | 8-10 |
HazardClass | 6.1(a) |
PackingGroup | II |
MSDS Information |
Provider | Language |
---|---|
Vinblastine sulfate | English |
SigmaAldrich | English |
ACROS | English |
Vinblastine sulfate Usage And Synthesis |
Chemical Properties | Crystalline Solid |
Usage | antineoplastic, spindle poison |
Usage | Labelled Vinblastine (V314000). Antitumor alkaloid isolated from periwinkle, Vinca rosea Linn., Apocynaceae; inhibits microtubule assembly. An antineoplastic. |
General Description | An anticancer drug. White to slightly yellow crystalline powder. |
Air & Water Reactions | Water soluble..Rapidly hydrolyzes. |
Reactivity Profile | Vinblastine sulfate is sensitive to light, hydrolysis, oxidation, and heat. Vinblastine sulfate is very hygroscopic. . |
Health Hazard | SYMPTOMS: Symptoms of exposure to Vinblastine sulfate include temporary mental depression, paresthesias, loss of deep-tendon reflexes, headache, convulsions, psychoses; dysfunction of the autonomic nervous system, with marked constipation, paralytic ileus, urinary retention, bilateral pain and tenderness of the parotid glands associated with dryness of the mouth, sinus tachycardia; nausea, vomiting, anorexia, diarrhea; loss of hair, vesicular mucositis of the mouth, and dermatitis. |
Fire Hazard | Flash point data for Vinblastine sulfate are not available; however Vinblastine sulfate is probably combustible. |
Biological Activity | Anticancer agent; microtubule disrupter. Induces apoptosis in cultured hepatocytes and human lymphoma cells. |
Vinblastine sulfate Preparation Products And Raw materials |
Preparation Products | DESACETYLVINBLASTINEAMIDE |