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HENAN SUNLAKE ENTERPRISE CORPORATION

Country: China (Mainland)

Business Type:Trading Company

Ms.summer

Tel: +86-371- 86259723

Mr.William

Tel: 17734809689

Ms.lisa

Tel: 17734809689

Ms.Tina

Tel: 86-371-86259723

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Tel: 17734809689

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Tel: 17734809689

Mobile: 17734809689

Tel: +86-371- 86259723

Fax: +86-371- 86259723

Province/state: HENAN

City: ZHENGZHOU

Street: Mingmen International Center, NO.222 Dongming Road,Zhengzhou,Henan,China

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KENPAULLONE

CAS NO.142273-20-9

  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/P,T/T,
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Product Details

Keywords

  • NSC-664704
  • KENPAULLONE
  • 9-BroMopaullone

Quick Details

  • ProName: KENPAULLONE
  • CasNo: 142273-20-9
  • Molecular Formula: C16H11BrN2O
  • Appearance: solid
  • Application: 142273-20-9
  • DeliveryTime: within 7-10days after receiving paymen...
  • PackAge: as required
  • Port: TIANJIN/SHANGHAI
  • ProductionCapacity: 100 Kilogram/Month
  • Purity: 99%
  • Storage: Room temperature
  • Transportation: by sea/ by express
  • LimitNum: 1 Kilogram

Superiority

Henan Sunlake Enterprise Corporation

Our Advantages

    1, Any inquiry about chemicals will be welome and replied within 24 hours;

    2, Competitive price;

    3, Good quality is guaranteed;

    4, Fast and safe delivery;

    5, Full experience in manufacture and international trade;

    6, Perfect and professional service.

 

 

Details

Product information 

KENPAULLONE Basic information
Product Name: KENPAULLONE
Synonyms: 9-BROMO-7,12-DIHYDRO-INDOLO[3,2-D][1]BENZAZEPIN-6(5H)-ONE;8-BROMO-7,12-DIHYDRO-INDOLO[3,2-D][1]-BENZAZEPIN-6(5H)-ONE;KENPAULLONE;NSC-664704;9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one, NSC 664704;9-bromo-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one;9-BroMopaullone;Kenpaullon
CAS: 142273-20-9
MF: C16H11BrN2O
MW: 327.18
EINECS:  
Product Categories: All Inhibitors;Inhibitors;Protein Kinase;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File: 142273-20-9.mol
KENPAULLONE Structure
 
KENPAULLONE Chemical Properties
Melting point  >300°C (dec.)
storage temp.  2-8°C
solubility  DMSO: 18 mg/mL, clear, yellow
color  yellow
CAS DataBase Reference 142273-20-9(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
MSDS Information
Provider Language
SigmaAldrich English
 
KENPAULLONE Usage And Synthesis
Chemical Properties Tan Solid
Usage The paullones are a novel class of kinase inhibitors, initially identified as CDK inhibitors. Kenpaullone has been found to be a useful GSK-3 inhibitor (IC50=23nM).
Biological Activity Potent inhibitor of CDK1/cyclin B and GSK-3 β (IC 50 values are 0.4 and 0.23 μ M respectively). Also inhibits CDK2/cyclin A, CDK2/cyclin E and CDK5/cyclin/p35 (IC 50 values are 0.68, 7.5 and 0.85 μ M respectively). Selective over c-src (IC 50 = 15 μ M), casein kinase 2 (IC 50 = 20 μ M), ERK1 (IC 50 = 20 μ M), ERK2 (IC 50 = 9 μ M) and a range of other protein kinases (IC 50 values > 35 μ M). Generates induced pluripotent stem cells (iPSCs) from somatic cells when used in combination with reprogramming factors; can replace Klf4.
 Company information

 Henan sunlake enterprise corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .

  Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs ,  Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East ,  Africa , South America and some other countries and areas.

    We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you  better with our high - quality products and professional team.

    We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.

    We  welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate.

 

 

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