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CAS NO.1400-61-9
| Nystatin Basic information |
| Product Name: | Nystatin |
| Synonyms: | MORONAL;MYCOSTATIN;MYCOSTATIN(R);NYSTATIN, STREPTOMYCES NOURSEI;NYSFUNGIN;NYSTATIN;biofanal;candio-hermal |
| CAS: | 1400-61-9 |
| MF: | C47H75NO17 |
| MW: | 926.09 |
| EINECS: | 215-749-0 |
| Product Categories: | Antibiotic Explorer;Antibiotics A to;Antibiotics N-SAntibiotics;AntibioticsAntibiotics;AntifungalAntibiotics;Cell Culture;Chemical Structure Class;Interferes with Cell Membrane Permeability (Ionophores)Antibiotics;Mechanism of Action;Polyenes;Reagents and Supplements;Spectrum of Activity;Antifungal;Carbohydrates & Derivatives;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;API;Mycostatin;antibiotic;Inhibitors |
| Mol File: | 1400-61-9.mol |
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| Nystatin Chemical Properties |
| mp | >155°C (dec.) |
| storage temp. | −20°C |
| solubility | H2O: insoluble |
| form | suspension |
| color | yellow |
| Merck | 13,6770 |
| Safety Information |
| Hazard Codes | F,C |
| Risk Statements | 11-34 |
| Safety Statements | 22-24/25-45-36/37/39-26-16 |
| WGK Germany | 3 |
| RTECS | RF5950000 |
| F | 10-8-23 |
| Hazardous Substances Data | 1400-61-9(Hazardous Substances Data) |
| Nystatin Usage And Synthesis |
| Chemical Properties | Brown Solid |
| Usage | Antifungal;Performs membrane ionophores |
| Usage | Nystatin is polyene antifungal containing a conjugated tetraene and a diene, isolated as a complex of three components A1, A2 and A3 from Streptomyces noursei and first reported in 1950. Nystatin, like most polyene antifungals, binds to sterols in the fungal cell membrane leading to formation of ion channels in the wall, ion imbalance and cell death. Nystatin is an established bioprobe and widely-used antifungal reagent with over 4,000 literature citations. |
| Usage | Polyene antifungal antibiotic complex containing 3 biologically active components, A1, A2, A3. Increases the permeability of the cell membrane of sensitive fungi by binding to sterols. Cell culture tested. Growth promotant. Nystatin A1 is shown. |
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