Keywords

• Voriconazole
• 137234-62-9
• C16H14F3N5O

Quick Details

• ProName: Voriconazole 137234-62-9
• CasNo: 137234-62-9
• Molecular Formula: C16H14F3N5O
• Appearance: detailed in specifcations
• Application: Aripiprazole Intermediate
• DeliveryTime: within 5days
• PackAge: as needed
• Port: China main port
• ProductionCapacity: 500 Metric Ton/Month
• Purity: 99%
• Storage: Keep in dry and cool condition
• Transportation: by air or sea
• LimitNum: 1 Kilogram
• MF: C13H21O3PS

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Company information

Henan Sunlake Enterprise Corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs , Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East , Africa , South America and some other countries and areas.We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you better with our high - quality products and professional team.We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.We welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate.

Details

Voriconazole Basic information

Product description Pharmacological interactions Application

Product Name:	Voriconazole
Synonyms:	2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1h-1,2,4-triazol-1-yl)butan-2-ol;VORICONAZOLE;(2R,3S/2S,3R)-3-(5-FLUORO-4-PYRIMIDINYL)-2-(2,4-DIFLUOROPHENYL)-1-(1H-1,2,4-TRIA;(aR,bS)-a-(2,4-Difluorophenyl)-5-fluoro-b-methyl-a-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol;UK-10949;Vorionazole;(2R,3S)-2-(2,4-DIFLUOROPHENYL)-3-(5-FLUOROPYRIMIDIN-4-YL)-1-(1H-1,2,4-TRIAZOL-1-YL)BUTAN-2-OL;(aR,S)-a-(2,4-Difluorophenyl)-5-fluoro--methyl-a-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol
CAS:	137234-62-9
MF:	C16H14F3N5O
MW:	349.31
EINECS:	200-261-5
Product Categories:	API;Antifungal (Systemic);Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics;Heterocycles;Pfizer compounds;Inhibitor;ZINACEF;Fine Chemical
Mol File:	137234-62-9.mol

Voriconazole Chemical Properties

mp	127-130°C
storage temp.	Store at +4°C
CAS DataBase Reference	137234-62-9(CAS DataBase Reference)

Safety Information

Hazard Codes	Xn,T,F
Risk Statements	22-36/38-52/53-48/22-40-25-61-39/23/24/25-23/24/25-11
Safety Statements	26-36-45-36/37-22-53-16

MSDS Information

 

Voriconazole Usage And Synthesis

Product description	Voriconazole is a broad-spectrum triazole antifungal ,it is primarily used for the treatment of progressive, possibly life-threatening infections in immune deficiency patients. Indications include: immunosuppressed patients with severe fungal infections, acute invasive aspergillosis (the most common pathogen is Aspergillus fumigatus, followed by A. flavus, Aspergillus niger and Aspergillus soil), severe invasive infections caused by fluconazole-resistant Candida (including C. krusei) severe infection caused by Foot actinomycetes bacteria genus and Fusarium bacteria genus . Moderate to severe renal insufficiency is administered intravenously paying caution.
Pharmacological interactions	Combination With the CYP3A4 substrates, terfenadine, sirolimus, astemizole, cisapride, pimozide or quinidine , can increase blood concentrations of this drug, leading to QT prolongation, and occasionally torsades de pointes ventricular tachycardia. Combination With Rifampicin, rifabutin, efavirenz, ritonavir (each 400mg, once every 12 hours), carbamazepine and phenobarbital, can significantly lower blood concentrations of voriconazole. Combination with ergot alkaloids (ergotamine, dihydroergotamine) plasma concentrations of ergot drugs can cause increased ergot poisoning. The above information is edited by the chemicalbook of Tian Ye.
Application	broad-spectrum antifungal
Chemical Properties	Cyrstalline Solid