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CAS NO.135062-02-1
| Repaglinide Basic information |
| Product Name: | Repaglinide |
| Synonyms: | AG-EE-623;2-ETHOXY-4-[2-[(1S)-3-METHYL-1-[2-(1-PIPERIDINYL)BUTYL]AMINO]-2-OXOETHYL]-BENZOIC ACID;REPAGLINIDE;(S)-2-ETHOXY-4-(2-(3-METHYL-1-(2-(PIPERIDIN-1-YL)PHENYL)BUTYLAMINO)-2-OXOETHYL)BENZOIC ACID;(S)-(+)-2-ETHOXY-4-[N-[1-(2-PIPERIDINOPHENYL)-3-METHYL-1-BUTYL]AMINOCARBONYLMETHYL]BENZOIC ACID;NOVONORM;PRANDIN;ag-ee388zw |
| CAS: | 135062-02-1 |
| MF: | C27H36N2O4 |
| MW: | 452.59 |
| EINECS: | |
| Product Categories: | Pharmaceutical material and intermeidates;Active Pharmaceutical Ingredients;Chiral Reagents;Amino Acids 13C, 2H, 15N;Chemical Impurities;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Amino Acids & Derivatives;Aromatics;Heterocycles;API;Pharmaceutical raw material;DTIC-DOME |
| Mol File: | 135062-02-1.mol |
|
|
|
| Repaglinide Chemical Properties |
| mp | 129-130.2 °C |
| storage temp. | 2-8°C |
| solubility | DMSO: 34 mg/mL |
| form | solid |
| color | white |
| CAS DataBase Reference | 135062-02-1(CAS DataBase Reference) |
| Safety Information |
| WGK Germany | 2 |
| RTECS | 000000033825 |
| MSDS Information |
| Provider | Language |
|---|---|
| Novonorm | English |
| SigmaAldrich | English |
| Repaglinide Usage And Synthesis |
| Chemical Properties | White to Off-White Solid |
| Usage | Non-sulfonylurea oral hypoglycemic agent. Used as an antidiabetic |
| Usage | The R-enantiomer showed only weak hypoglycemic activity. Repaglinide impurity |
| Usage | antineoplastic |
| Usage | A KIR6 (KATP) channel blocker |
| Biological Activity | K ATP channel blocker that binds with high affinity for SUR1 when co-expressed with Kir6.2 (K d = 0.42 nM). Antidiabetic glucose regulator with hypoglycaemic effect in vivo . |
| Repaglinide Basic information |
| Product Name: | Repaglinide |
| Synonyms: | AG-EE-623;2-ETHOXY-4-[2-[(1S)-3-METHYL-1-[2-(1-PIPERIDINYL)BUTYL]AMINO]-2-OXOETHYL]-BENZOIC ACID;REPAGLINIDE;(S)-2-ETHOXY-4-(2-(3-METHYL-1-(2-(PIPERIDIN-1-YL)PHENYL)BUTYLAMINO)-2-OXOETHYL)BENZOIC ACID;(S)-(+)-2-ETHOXY-4-[N-[1-(2-PIPERIDINOPHENYL)-3-METHYL-1-BUTYL]AMINOCARBONYLMETHYL]BENZOIC ACID;NOVONORM;PRANDIN;ag-ee388zw |
| CAS: | 135062-02-1 |
| MF: | C27H36N2O4 |
| MW: | 452.59 |
| EINECS: | |
| Product Categories: | Pharmaceutical material and intermeidates;Active Pharmaceutical Ingredients;Chiral Reagents;Amino Acids 13C, 2H, 15N;Chemical Impurities;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Amino Acids & Derivatives;Aromatics;Heterocycles;API;Pharmaceutical raw material;DTIC-DOME |
| Mol File: | 135062-02-1.mol |
|
|
|
| Repaglinide Chemical Properties |
| mp | 129-130.2 °C |
| storage temp. | 2-8°C |
| solubility | DMSO: 34 mg/mL |
| form | solid |
| color | white |
| CAS DataBase Reference | 135062-02-1(CAS DataBase Reference) |
| Safety Information |
| WGK Germany | 2 |
| RTECS | 000000033825 |
| MSDS Information |
| Provider | Language |
|---|---|
| Novonorm | English |
| SigmaAldrich | English |
| Repaglinide Usage And Synthesis |
| Chemical Properties | White to Off-White Solid |
| Usage | Non-sulfonylurea oral hypoglycemic agent. Used as an antidiabetic |
| Usage | The R-enantiomer showed only weak hypoglycemic activity. Repaglinide impurity |
| Usage | antineoplastic |
| Usage | A KIR6 (KATP) channel blocker |
| Biological Activity | K ATP channel blocker that binds with high affinity for SUR1 when co-expressed with Kir6.2 (K d = 0.42 nM). Antidiabetic glucose regulator with hypoglycaemic effect in vivo . |